American politicians talk about persecuted Christians abroad – but here’s what happens when those Christians migrate to the US

Source: The Conversation – USA (3) – By Candace Lukasik, Assistant Professor of Religion, Mississippi State University

Coptic Easter liturgy, East Brunswick, N.J., April 2017. Candace Lukasik, CC BY-SA

Two months ago, Terez Metry arrived at a Department of Homeland Security office in Nashville with her husband, a U.S. citizen, expecting a routine step in beginning her green card application. The couple had prepared documents for a Form I-130 petition and anticipated an interview about their marriage.

But the appointment took a different turn. Instead of leaving together, immigration officers detained Metry and transferred her to an immigration detention facility in Alabama.

Metry’s family had fled Egypt during the Arab Spring – the 2011 wave of uprisings across the Middle East and North Africa – and came to the United States when she was a teenager. Their asylum claim was denied, and Metry was unaware that a removal order had been issued when she was 13. She is now 28.

Metry is a Coptic Christian. Copts belong to one of the oldest Christian communities in the world and make up about 10% of Egypt’s population.

A majority of Coptic Christians live in Egypt. They face discrimination and periodic violence; they are often described in political, religious, and advocacy discourse as a persecuted minority. This framing has generated concern among many American Christians and spurred political mobilization on their behalf.

Yet, as Metry’s case reveals, such concern does not translate into preferential treatment: When these Christians arrive in the U.S., they are subject to the same immigration system that detains and deports other migrants.

I am an anthropologist of religion who has spent more than a decade studying Coptic Orthodox Christian migration between Egypt and the U.S. Between 2016 and 2022, I conducted fieldwork and interviews with Coptic migrants for my book, “Martyrs and Migrants.” I spoke with diversity visa applicants in rural Upper Egypt, asylum-seekers in New York courtrooms, and working-class communities in Nashville, Tennessee.

Across these sites, my research shows how two realities – the narrative of Christian persecution abroad and the suspicion surrounding migrants in the U.S. – collide in the lives of Copts themselves.

The global politics of persecution

Over the past two decades, attacks on churches and episodes of sectarian violence in Egypt have drawn international attention. These concerns intensified after the Arab Spring uprisings and escalated with the rise of militant organizations such as the Islamic State group.

In 2015, Islamic State group militants executed 21 Christian migrant workers – 20 Egyptian Copts and one Ghanaian man – on a beach in Libya. Images of their deaths quickly became potent symbols of Christian suffering across global media and church networks.

While Coptic Christians have long faced discrimination and intermittent violence in Egypt, attacks during this period intensified in both scale and public visibility.

People standing in the pews of a large cathedral with several coffins laid out in the front.
A funeral service in Cairo, Egypt, on Dec. 12, 2016, for victims of a bombing.
AP Photo/Nariman El-Mofty

In 2017 alone, the Islamic State group claimed responsibility for two bombings of churches in Egypt on Palm Sunday as well as the mass shooting of pilgrims traveling to a monastery in southern Egypt. Accounts of the victims circulated widely online and received international news coverage.

In the U.S., evangelical leaders, advocacy organizations and some politicians often talk about the “persecuted church” – a framework that became especially influential in American religious freedom activism from the 1990s onward. Churches, nonprofits and policy advocates highlighted violence against Christians abroad through media campaigns, prayer initiatives and political lobbying, presenting it as a global crisis requiring American attention.

At a 2017 summit in Washington, D.C., for example, evangelical leader Franklin Graham described violence against Christians in the Middle East and Africa as a “Christian genocide,” urging believers to recognize the scale of the threat and respond collectively.

In my research attending international religious freedom conferences in Washington D.C., I found that stories like these helped many American Christians feel a strong sense of connection to Christians in the Middle East, whose suffering was often understood as part of a broader global struggle facing Christianity.

Yet this powerful narrative sits uneasily alongside how Middle Eastern Christians are treated in the U.S., where they may encounter not protection but the everyday suspicions faced by migrants from the region.

When Coptic Christian migrate

In Egypt, Copts live as a religious minority in a Muslim-majority society, where they have long faced restrictions on building and repairing churches – often requiring state permits that are difficult to obtain. Additionally, they are underrepresented in state institutions such as the military, judiciary and senior government positions; they also face periodic episodes of sectarian violence.

Moving to the U.S., a country where Christianity is the majority religion, might seem like a natural refuge.

But migration often reveals a different reality.

In 2019, for example, Romany Erian Melek Hetta, a Coptic Christian asylum-seeker, visited the Museum of the Bible in Washington, D.C. According to media reports, while waiting for a friend outside the museum, security officers questioned him about his identity and later reported him to the FBI as a possible security threat. This triggered a counterterrorism investigation.

Cases like this echo patterns I encountered in my ethnographic research among Coptic migrants in the New York–New Jersey area, who frequently described being perceived as suspicious or potentially threatening in everyday encounters. Some altered their dress, names or public presentation to avoid being mistaken for Muslim or Arab. As one priest in my fieldwork recalled of the period after 9/11, “We had the wrong complexion … You felt like you were a target and it wasn’t your fault.”

In everyday life in the U.S., Coptic migrants like Hetta are often seen simply as people from the Middle East. As scholars of post-9/11 racialization have shown, people taken to be Arab or Middle Eastern were widely cast as potential security threats, regardless of their religious identity.

For example, Magdy Beshara was the Coptic owner of the St. George’s Shell gas station in Bayville, New Jersey. Shortly after 9/11, the FBI came to the family’s home in the middle of the night, asking Beshara whether Marwan al-Shehhi, one of the 9/11 hijackers, had worked at the gas station.

For my book I interviewed Beshara’s stepson, who described the aftermath of the initial FBI raid: “People would drive by and say ‘We’re going to kill you terrorists’ and throw a big liquor bottle at me and my sister.”

Under the USA Patriot Act – a law passed after 9/11 that expanded the federal government’s surveillance and search powers – agents confiscated items from the family’s gas station and home. According to Beshara’s stepson, their mail was opened, their phones were tapped and they were followed to school by federal agents. The family also reported receiving death threats and said that when they asked local police to intervene, their requests were not acted upon.

Beshara’s stepson told me the experience forced him to draw a distinction. “It made me feel weird to say out loud, but I always thought to myself, ‘I’m not a Muslim, I’m a Christian.’ I felt like I was putting them down to say, ‘Hey, look, I’m the good guy.’ I felt like we had to do anything to defend ourselves.”

At school, he was bullied and physically assaulted on dozens of occasions. At one point in the months following the raid, an unknown assailant set the family’s house on fire while he and his little sister were sleeping. All of this took place even after the FBI notified Beshara that he was no longer a subject of investigation, since al-Shehhi, in fact, did not work at the gas station.

Even though Beshara was a Christian, that did not shield him from suspicion or discrimination. Government surveillance tied to counterterrorism and prejudice from neighbors continued to shape how he was seen.

A grey-haired man in a grey suit and red tie walks beside another in a priestly robe and long flowing beard, with an entourage behind them.
Former U.S. President Jimmy Carter with Pope Shenuda III, patriarch of the Coptic Orthodox Church, on March 21, 1987, in Cairo, Egypt.
AP Photo/Paola Crociani

Between persecution and suspicion

These dynamics become especially visible in moments of enforcement, where the gap between political rhetoric and immigration policy comes into sharp relief.

In 2017, federal immigration raids detained Iraqi nationals across the U.S., many of them Chaldean Christians – an Eastern Catholic community from Iraq with ancient roots in Mesopotamia.

These arrests prompted a class action lawsuit on behalf of those detained in the Detroit area, which was later expanded to include roughly 1,400 Iraqi nationals nationwide with final deportation orders.

Such cases unfold even as American Christians continue to say Middle Eastern Christians are uniquely deserving of protection – a disconnect between advocacy for “persecuted Christians” abroad and the realities of immigration enforcement at home.

In my own work as an expert witness for Coptic asylum-seekers, I have observed similar patterns across a detention system stretching from New Jersey to Louisiana. Some migrants are released while their cases proceed; others remain in prolonged legal limbo.

What I have found is that in practice, the line between “persecuted Christian” and “suspect migrant” is not just blurred – it is continually being redrawn by the state and reproduced in everyday encounters.

The Conversation

Candace Lukasik received funding from the Social Science Research Council, the American Academy of Religion, the Louisville Institute, and the Orthodox Christian Studies Center at Fordham University.

ref. American politicians talk about persecuted Christians abroad – but here’s what happens when those Christians migrate to the US – https://theconversation.com/american-politicians-talk-about-persecuted-christians-abroad-but-heres-what-happens-when-those-christians-migrate-to-the-us-276186

Two verdicts in two days: How American courts are rewriting the rules for Big Tech and children

Source: The Conversation – USA (3) – By Carolina Rossini, Professor of Practice and Director for Program, Public Interest Technology Initiative, UMass Amherst

Judge Bryan Biedscheid of New Mexico could order significant changes to how Instagram and Facebook operate. Nathan Burton/Santa Fe New Mexican via AP, Pool

Within 48 hours, the legal landscape governing social media and children shifted in ways that will take years to fully understand and verify.

On March 24, 2026, a Santa Fe jury ordered Meta to pay US$375 million for violating New Mexico’s consumer protection laws. The next day, a Los Angeles jury found Meta and Google’s YouTube negligent in the design of their platforms, awarding almost $6 million in damages to a single plaintiff.

The dollar figures are drawing headlines, but a $375 million penalty against a company worth $1.5 trillion is a rounding error. The award is less than 2% of Meta’s $22.8 billion net income in 2025. Meta’s stock rose 5% on the day of the New Mexico verdict, indicating how the market assessed the effect of the penalty on the company.

Fines without structural change are more akin to licensing fees than accountability. As a technology policy and law scholar, I believe the question of whether these verdicts will produce real changes to the products that millions of children use every day is more consequential than the jury awards.

The answer is not yet, and not automatically. A financial penalty does not rewrite a single line of code, remove an algorithm or place a safety engineer in a role that was eliminated to protect a quarterly earnings report. Meta and Google have signaled they will appeal, with First Amendment challenges to the product-design theory the likely central battleground.

The companies’ lawyers are likely to argue, with some justification, that the science linking the design of platforms to mental health harm remains contested, and that the companies have already implemented safety measures. In the meantime, Instagram, Facebook anf YouTube will continue to operate exactly as they did before the verdicts.

The verdicts against Meta pave the way for hundreds or even thousands of similar cases.

Consumer protection

Most coverage framing the New Mexico verdict casts it as a child safety case. It is that, but it also presents a more technically significant dimension: a consumer protection claim grounded in allegations of corporate deception. New Mexico Attorney General Raúl Torrez did not sue Meta for what users posted, but instead sued Meta for its false statements about its own platform safety, employing a novel legal approach.

For three decades, Section 230 of the Communications Decency Act has shielded internet platforms from liability for content generated by their users. Courts have interpreted Section 230 immunity broadly, and many earlier attempts to hold platforms accountable for child harm have foundered on it.

The New Mexico complaint, filed in December 2023, was drafted with explicit awareness of this obstacle. It asked a single question: Did Meta knowingly lie to New Mexico consumers about the safety of its products?

The jury’s answer was yes, on all counts, and its verdict rested on three distinct legal theories under New Mexico’s Unfair Practices Act.

The first was straightforward deception: Meta’s public statements, ranging from CEO Mark Zuckerberg’s congressional testimony claiming research about the platform’s addictiveness was inconclusive to parental guidance materials that omitted known risks of grooming and sexual exploitation, qualify as representations made in connection with a commercial transaction.

Users pay for Meta’s platforms not with money but with their data, which Meta then converts into advertising revenue. New Mexico successfully argued that this data-for-services exchange constitutes commerce under the state’s consumer protection statute, and that misrepresentations made within it are actionable regardless of Section 230.

The second theory was unfair practice, or conduct offensive to public policy, even if not technically deceptive. Here, the evidence centered on what Meta’s own engineers and executives knew and then ignored.

Internal documents showed repeated warnings. These alarm bells centered around child sexual abuse material proliferating on the platforms, about algorithms that amplified harmful content because it generated engagement, and about age verification systems that were essentially cosmetic. The company overrode those warnings for commercial reasons.

The jury was shown a specific sequence: Meta executives requested staffing to address platform harms, Zuckerberg declined, and the company continued to publicly represent its safety efforts as adequate.

The third theory was unconscionability: taking advantage of consumers who lacked the capacity to protect themselves. Children are the clearest possible case. Children cannot evaluate terms of service, cannot negotiate platform architecture, and cannot assess the neurological implications of engagement-maximizing design. Meta had comprehensive internal research documenting these vulnerabilities and chose to ignore rather than mitigate them.

Bellwether on addictiveness

The Los Angeles case, which concluded on March 25, tested a different theory. It was a personal injury trial rather than a government enforcement action.

The plaintiff, identified in court as KGM, is a 20-year-old woman who began using YouTube at age 6 and Instagram at age 9. Her lawyers argued that the platforms’ deliberate design choices such as infinite scroll, autoplay video and engagement-based recommendation algorithms were the causes of her addiction, depression and self-harm.

The jury found both Meta and YouTube negligent in the design of their platforms and found that each company’s negligence was a substantial factor in causing harm to KGM. Meta bears 70% of the liability; YouTube 30%. The individual $3 million compensatory award is modest. The punitive damages phase, still to come, will be calculated against each company’s net worth and is likely to produce a very different number.

six woman seated outside a building have facial expressions indicating surprise and happiness
An attorney for, and family members of, child victims of social media harms react to the verdict in a lawsuit in Los Angeles on March 25, 2026.
Frederic J. Brown/AFP via Getty Images

Beyond the general precedent, this case matters because it is a bellwether. It was selected from a consolidated group of hundreds of similar lawsuits to test whether a product-design theory of liability could survive a jury trial, and it did. That finding has immediate and concrete implications: Each of those plaintiffs now litigates on a stronger footing, and if the damages awarded to KGM are even partially scaled across similar cases, the total financial exposure for Meta and YouTube moves from hundreds of millions to billions of dollars.

More importantly, the bellwether verdict signals to every other plaintiff, attorney and state attorney general that this legal pathway is viable, and to every platform that the courtroom is no longer a safe harbor. The legal strategy established that negligence claims against platform design are viable in California courts.

Public nuisance

Beginning May 4, 2026, Judge Bryan Biedscheid in the New Mexico case is scheduled to hear the public nuisance count without a jury in a bench trial. Public nuisance is a legal doctrine traditionally used to address conditions that harm the general public. This doctrine has been used in concern over contaminated water, lead paint in housing stock and opioid distribution networks.

New Mexico is arguing that Meta’s platform architecture constitutes exactly such a condition. If the judge agrees, the remedy is not a fine. Instead, it is an abatement: a court order requiring Meta to eliminate the harmful condition.

Attorney General Torrez has already been explicit about what he will ask for: real age verification, not a checkbox asking users to confirm they are old enough; algorithm changes; and an independent monitor with authority to oversee compliance. These are structural demands on how the platform operates.

This is where drawing a parallel with Big Tobacco is apt. The tobacco litigation of the 1990s ultimately produced not just financial settlements but the Master Settlement Agreement, which imposed permanent restrictions on marketing practices and funded public health programs for decades. The public nuisance theory in the New Mexico case is designed to produce an analogous structural outcome for social media.

Precedent for tidal wave of cases

The significant effects of two verdicts are about evidence and precedent. For the first time, a jury has examined Meta’s internal documents – emails from engineers warning about self-harm, the rejected safety proposals and Zuckerberg’s personal decisions to prioritize engagement over protection – and returned a verdict that those documents mean precisely what they appear to say.

That finding, and the legal theories that produced it, is now part of the foundation on which 40-plus pending state attorney general cases, thousands of individual lawsuits and a federal trial later this year are likely to be built.

The abatement phase, beginning May 4, may prove more consequential than the dollar amounts. If the judge in the New Mexico case – or any judge in a subsequent case – orders real age verification, algorithm changes and an independent monitor, that would be a true structural change.

The Conversation

I was staff at organizations including the Electronic Frontier Foundation, Public Knowledge, and the Harvard Berkman Klein Center, which were funded by various foundations and companies. Refer to their websites for disclosures. I was a staff member in the connectivity policy team at Facebook (2016-2018). I am an advisory board member of non-profits, including Internet Lab (Brazil) and Derechos Digitales (Chile). I am a senior advisor (without any honorarium) at the Datasphere Initiative and Portulans Institute. More details at https://www.carolinarossini.net/bio

ref. Two verdicts in two days: How American courts are rewriting the rules for Big Tech and children – https://theconversation.com/two-verdicts-in-two-days-how-american-courts-are-rewriting-the-rules-for-big-tech-and-children-279401

I went to CPAC and found Trump supporters unhappy about Iran, Epstein files and the economy, even while the fans at the MAGA conference celebrate his immigration policies

Source: The Conversation – USA – By Alex Hinton, Distinguished Professor of Anthropology; Director, Center for the Study of Genocide and Human Rights, Rutgers University – Newark

Attendees wearing MAGA merch stand next to an image of Trump at the Conservative Political Action Conference in Grapevine, Texas, on March 25, 2026. Leandro Lozada AFP/Getty Images

There is a pall over the Make America Great Again, or MAGA, movement. Donald Trump overpromised. His public support has fallen. Some “America First” die-hards now openly criticize him.

Amid war, economic challenges, democratic backsliding, the Epstein files and Americans shot dead in the street by government agents, Trump’s support is softening and his vow to bring a “golden age of America” is looking more like a political winter for Trump and his MAGA movement.

This is my big takeaway from this year’s annual Conservative Political Action Conference, or CPAC. The event, organized by the American Conservative Union, launched with an international summit on March 25, 2026, and runs through March 28 in Grapevine, Texas.

Don’t get me wrong. The attendees are decked out in red, white and blue MAGA merch: sequined “Trump” purses and jackets, USA flag bags, ties and headbands, and, of course, iconic red MAGA caps. As always, they chant “USA,” even if not as often or as loudly as before.

Starting with the first talk by Rev. Franklin Graham, speakers here are still singing Trump’s praises. They underscore what they regard as major Trump 2.0 accomplishments: combating illegal immigration, cutting taxes, a budding economic boom, deregulation, U.S. gas and oil output surging, administrative state winnowing, pro-Christian policies and pulling the plug on the “woke” agenda.

These issues are foregrounded in sessions with titles like “Walls Work,” “Don’t Let Woke Marxists Raise Your Children,” “MAGA vs. Mullah Madness,” “Commies Go Home” and “Cancelling Satan.” In between, pro-Trump advertisements checklist Trump’s accomplishments.

This rose-tinted view is to be expected. After all, CPAC – a cross between a political rally, networking mixer and MAGA Comic-Con – is all about galvanizing the conservative base. Beneath the surface, however, MAGA is churning.

A man wearing a skullcap with a photo of Donald Trump on it stands at a table in a conference hall.
An attendee visits a stand at the Conservative Political Action Conference in Grapevine, Texas, on March 26, 2026.
Leandro Lozada/AFP via Getty Images

Major grievances

An anthropologist of American political culture and author of the book “It Can Happen Here,” I have been studying MAGA for years and attending CPAC since 2023. Attendees at last year’s CPAC, held a month after Trump’s inauguration, were jubilant, with nonstop talk of “the comeback kid” and “the golden age.”




Read more:
I went to CPAC as an anthropologist to see how Trump supporters are feeling − for them, a ‘golden age’ has begun


Why is the mood at this year’s CPAC more subdued?

Enthusiasm for Trump is dampened because some of his supporters feel he has betrayed America First principles, failed to fulfill key campaign promises and been unable to supercharge the economy. Here are their major grievances:

‘America First’ vs. ‘Israel First’

America First” is the guiding principle of MAGA. It encompasses border security, prioritizing the U.S. economy and ensuring rights such as free speech. It also means avoiding unnecessary wars.

This is why Trump’s support of the June 2025 “12-day war” on Iran led Tucker Carlson, Marjorie Taylor Greene and other MAGA influencers, who have tens of millions of followers, to criticize Trump. The conflict, they contend, served Israel’s interest – their phrase is “Israel First” – not those of the U.S.

Their criticisms became even more pronounced after the U.S. again began bombing Iran on Feb. 28, 2026. The criticism is part of a growing MAGA fissure with pro-Israel stalwarts such as conservative activists Mark Levin, Laura Loomer and Ben Shapiro, who support U.S. intervention in the Middle East. Things got so bad that after Levin called his fellow conservative media personality Megyn Kelly “unhinged, lewd and petulant,” she dubbed him “Micropenis Mark.”

A man casually dressed in a t-shirt, plaid shirt over that, a black baseball cap and sunglasses stands in a convention center room.
Former Proud Boys chairman Enrique Tarrio is seen at CPAC in Grapevine, Texas, on March 25, 2026.
Leandro Lozada/AFP via Getty Images

But the MAGA unease with the war extends well beyond the “America First” influencers.

It includes figures from the fringe far right such as provocateur Nick Fuentes, center-right “brocaster” Joe Rogan, and even the Trump administration itself – as illustrated by an intelligence officer whose resignation stated, “Iran posed no imminent threat to our nation, and it is clear that we started this war due to pressure from Israel and its powerful American lobby.”

Notably, none of the main Trump critics have been scheduled to speak at this year’s CPAC. Some now call it “TPAC,” or the Trump Political Action Conference.

The Epstein files

MAGA also has a strong populist and anti-elite streak of conspiracy thinking.

Large numbers of Trump supporters, for example, believe there is an elite plot to what they call “replace” the white population with nonwhites through mass immigration. Many also bought into the QAnon conspiracy theory, which centers on the idea that Trump is fighting Satanic, deep state elites who are running a child sex trafficking operation.

On the campaign trail, Trump vowed to take down political, deep state and global elites. He also promised to release the Jeffrey Epstein files, which QAnon conspiracists and others believe prove elite debauchery, including pedophilia.

Trump didn’t deliver. He backtracked and stonewalled on the release of the Epstein files, raising MAGA suspicion that Trump himself is implicated or is protecting elites. Remarkably, one recent poll found that roughly half of Americans, including a quarter of Republicans, believe the Iran war was partly meant to distract from the Epstein files.

Economy and immigration

Trump is also facing headwinds on the bread-and-butter issues of the 2024 election: the economy and immigration.

At CPAC, speakers have repeatedly given him kudos for shutting down the border. Acknowledging the MAGA in-fighting, conservative commentator Benny Johnson said he wanted to “white pill” – or buck up – the audience by reminding them that Trump had stopped an “invasion” and brought “criminal alien border crossings down to zero.”

As a photo of Trump’s bloodied face after the assassination attempt in Butler, Pennsylvania, on July 13, 2024, was displayed, Johnson claimed, “Our God saved President’s Trump’s life for this moment.”

But fewer Republicans approve of his handling of immigration compared with a year ago. Like many Americans, a growing number have misgivings about the strong-arm tactics used by government immigration enforcement agents in places such as Minnesota.

For many, the economy remains a serious worry. A recent poll, conducted before the Iran war, found that the vast majority of Americans, including large numbers of Republicans, are concerned about inflation, jobs and the cost of living. Health care, including the lost Obamacare subsidies, is also a source of consternation.

Few people believe the economy is “booming” – let alone that a “golden age” has arrived – as Trump and his allies often proclaim. The war with Iran, which has led to stock market declines and gas pump hikes, has only added to the unease.

MAGA ‘shattered’?

Amid the recent MAGA in-fighting about the Iran war, conservative podcaster Tim Pool proclaimed, “The MAGA coalition is shattered.”

Not exactly. Despite the many challenges Trump is facing, the vast majority of his MAGA base voters still support him – including almost 90% backing his war with Iran.

But Trump’s support has eased in several ways. First, even his hardcore supporters worry about the economy, and they want him to declare victory and exit the war. And second, Trump has lost support on the edges. Many people in the key groups with which he made crucial inroads in the last election – such as young men and nonwhite voters – have turned from him. The same is true for independents and other Trump voters who don’t identify as MAGA.

Trumpism isn’t dead, as the MAGA-merched crowds here at CPAC make clear. But Trump is struggling through a political winter that could signal the early stages of his MAGA movement’s decline.

The Conversation

Alex Hinton receives funding from Alex Hinton receives funding from the Rutgers-Newark Sheila Y. Oliver Center for Politics and Race in America, Rutgers Research Council, and Henry Frank Guggenheim Foundation.

ref. I went to CPAC and found Trump supporters unhappy about Iran, Epstein files and the economy, even while the fans at the MAGA conference celebrate his immigration policies – https://theconversation.com/i-went-to-cpac-and-found-trump-supporters-unhappy-about-iran-epstein-files-and-the-economy-even-while-the-fans-at-the-maga-conference-celebrate-his-immigration-policies-278856

Mosquitoes carrying malaria are evolving more quickly than insecticides can kill them – researchers pinpoint how

Source: The Conversation – USA – By Jacob A Tennessen, Research Scientist in Immunology and Infectious Diseases, Harvard University

_Anopheles darlingi_, a key carrier of malaria, is rapidly evolving resistance to insecticides. Romuald Carinci and Pascal Gaborit/Duchemin lab/Institut Pasteur de la Guyane, CC BY-SA

The fight against infectious disease is a race against evolution. Bacteria become resistant to antibiotics. Viruses adapt to spread more quickly. Diseases transmitted by insects present another evolutionary front: Insects themselves can evolve resistance to the poisons that people use to kill them.

In particular, the mosquito-borne disease malaria kills over 600,000 people annually. Since World War II, people have battled malaria with insecticides – chemical weapons intended to kill Anopheles mosquitoes infected with the Plasmodium parasites that cause the disease.

However, mosquitoes are quickly evolving counterstrategies that make these insecticides ineffective, putting millions of people at greater risk of deadly infection. My colleagues and I have newly published research showing how.

Insecticide resistance threatens public health

As an evolutionary geneticist, I study natural selection – the basis for adaptive evolution. Genetic variants that best promote survival can replace less advantageous versions, causing species to change. Anopheles mosquitoes are frustratingly adept at evolving.

In the mid-1990s, most African Anopheles were susceptible to pyrethroids, a popular type of insecticide originally derived from chrysanthemums. Anopheles control relies on two pyrethroid-based methods: insecticide-treated bed nets to protect sleepers, and indoor residual spraying of insecticide against the walls of homes. These two methods alone likely prevented over a half-billion cases of malaria between 2000 and 2015.

However, mosquitoes today from Ghana to Malawi are often able to survive insecticide concentrations 10 times the previously lethal dose. Along with Anopheles control efforts, agriculture also inadvertently exposes mosquitoes to pyrethroids and contributes to insecticide resistance.

In some African locales, Anopheles is already showing resistance to all four main classes of insecticide used for malaria control.

Close-up of mosquito on human skin with abdomen engorged with blood, a droplet extruding at its end
Anopheles mosquitoes are found all over the world.
Jim Gathany/CDC

Adaptation in Latin American mosquitoes

Anopheles mosquitoes and the malaria-causing Plasmodium also occur outside Africa, where insecticide resistance is less well-researched.

In much of South America, the main malaria vector is Anopheles darlingi. This mosquito species has diverged evolutionarily from the African vectors so extensively that it might be a different genus, Nyssorhynchus. Along with colleagues from eight countries, I analyzed over 1,000 Anopheles darlingi genomes to understand its genetic diversity, including any recent changes due to human activity. My collaborators collected these mosquitoes at 16 locations ranging from the Atlantic coast of Brazil to the Pacific side of the Andes in Colombia.

We found that, like its African counterparts, Anopheles darlingi shows extremely high genetic diversity – more than 20 times that of humans – indicating that very large populations of this insect exist. A species with such a vast gene pool is well poised to adapt to new challenges. The right mutation giving it the advantage it needs is more likely to pop up when there are so many individuals. And once that mutation starts to spread, it’s protected by numbers since it won’t be wiped out if a few mosquitoes die by chance.

In contrast, bald eagles in the contiguous U.S. were never able to evolve resistance against the insecticide DDT and approached extinction. Evolution is more efficient among millions of insects than mere thousands of birds. And indeed, we saw signals of adaptive evolution in the resistance-related genes of Anopheles darlingi occurring over the past few decades.

Mosquitoes evolve to detoxify poisons

Insecticides like pyrethroids and DDT share the same molecular target: channels in nerve cells that can open and close. When open, the nerve cell stimulates other cells. These insecticides force the channels to remain open and continuously fire, causing paralysis and death. However, insects can evolve resistance by changing the shape of the channel itself.

Earlier genetic scans performed by other researchers had not detected this type of resistance in Anopheles darlingi, and neither did ours. Instead, we found that resistance is evolving in another way: a group of genes encoding enzymes that break down toxic compounds. High activity of these enzymes, called P450, frequently underlies resistance to insecticides in other mosquitoes. The same cluster of P450 genes has changed independently at least seven times across South America since insecticide use began in the mid-20th century.

In French Guiana, a different set of P450 genes exhibits a similar evolutionary pattern, cementing the clear connection between these enzymes and adaptation. Moreover, when we exposed mosquitoes to pyrethroids in sealed bottles, differences among the P450 genes of individual mosquitoes were linked to the length of time they stayed alive.

Insecticide-heavy campaigns against malaria have been only sporadic in South America and may not be the main driver behind this evolution. Instead, it’s possible that mosquitoes are being exposed indirectly to agricultural insecticides. Intriguingly, we saw the strongest signs of evolution in places where farming is prevalent.

Diagram comparing Mendelian inheritance (50% chance of inheritance leads to slower spread) with gene drive inheritance (nearly 100% inheritance leads to rapid spread)
Gene drives can help a malaria-fighting mutation spread more quickly through a mosquito population than it would by chance alone.
Naidoo et al./Gene Therapy, CC BY-SA

Toward more sophisticated vector control

Despite new vaccines and other recent advances against malaria, mosquito control remains essential for reducing disease.

Some countries are launching trials of gene drives to control malaria, which involve forcing a genetic modification into a mosquito population to reduce their numbers or their tolerance for Plasmodium. Such prospects are exciting, though the relentless adaptability of mosquitoes could be an obstacle.

I and others are revising methods to efficiently test for emerging insecticide resistance. Genome-scale sequencing remains important to detect new or unexpected evolutionary responses. The risk of adaptation is highest under a continuous, strong selection pressure, so minimizing, switching and staggering pesticides can help thwart resistance.

Success in the fight against evolving resistance will require a coordinated effort of monitoring, and reacting accordingly. Unlike evolution, humans can think ahead.

The Conversation

Jacob A Tennessen receives funding from the National Institutes of Health via Harvard T.H. Chan School of Public Health and the Broad Institute.

ref. Mosquitoes carrying malaria are evolving more quickly than insecticides can kill them – researchers pinpoint how – https://theconversation.com/mosquitoes-carrying-malaria-are-evolving-more-quickly-than-insecticides-can-kill-them-researchers-pinpoint-how-275391

Millions are protesting – but boycotts might be key to changing government policies

Source: The Conversation – USA (2) – By Lisa Schirch, Professor of the Practice of Peace Studies, University of Notre Dame

The ‘No Kings’ protests have drawn millions of Americans and may grow even larger. Frederic J. Brown/AFP via Getty Images

The organizers of the estimated 3,000 “No Kings” protests, rallies and other events planned for March 28, 2026, say they expect that the protests will be the largest such mass mobilization in U.S. history.

As scholars of peace studies and social movements, we investigate how ordinary people press their governments to change their policies.

An estimated 7 million Americans took part in the 2,100 “No Kings” protests on Oct. 18, 2025, breaking all previous records. But research that we and other scholars have conducted indicates that massive turnouts at protests may not be enough to achieve the goals of a protest movement, such as bringing about changes in government policies.

We believe that protest movements can be more effective when they place more emphasis on boycotts of corporations that support a government’s agenda than on increasing the size and scope of these protests.

That’s because history suggests that boycotts are uniquely suited to expand public participation and reach the scale necessary for political change. Boycotts attract first-time activists with simple “buy this, not that” instructions. They offer easy ways for people to feel heard with little investment of time, money or risk.

Rise of the ‘No Kings’ movement

The “No Kings” movement has been holding nonviolent protests across the U.S. since June 2025 to express mass opposition to the Trump administration’s policies.

Its organizers include a range of nonprofits. They include those supporting civil rights, such as the American Civil Liberties Union; LGBTQ+ rights, like the Human Rights Campaign; progressive political groups, including Indivisible and MoveOn; and unions, such as the American Federation of Teachers.

The protests’ organizers are harnessing growing public opposition to President Donald Trump’s second administration. Gallup’s final presidential poll, for example, conducted in December 2025, found that only about 1 in 3 Americans approved of his performance.

In March 2026, Fox News found that 6 in 10 Americans disapprove of Trump’s immigration enforcement effort, and a CBS poll found that 6 in 10 oppose the U.S. war with Iran.

The “No Kings” movement from the start has objected to harsh federal immigration enforcement tactics, including the rapid growth in the number of immigrants being detained and deported. The March 28 protests will also make the widespread opposition to the costly Iran war more visible.

“No Kings” organizers cite other reasons for their protests, such as the White House’s threats to intervene in elections, health care spending cuts and the cessation of many environmental protections.

Four protesters, some in costumes, stand next to a huge American flag.
Many of the ‘No Kings’ events on Oct. 18, 2025, took place in small towns, like Shelburne, Vt., pictured here.
Robert Nickelsberg/Getty Images

Opposition to Trump is spreading

The “No Kings” protests have spread to more parts of the United States than ever before.

Protests have taken place in every state – in large cities like Dallas, Philadelphia and Phoenix, as well as thousands of smaller towns like Corydon, Indiana, and Hamilton, Montana. The protests even drew thousands of people in some GOP strongholds.

Researchers find that only a small part of the population needs to protest, boycott or strike to create strong pressure. If 3.5% of a population participates in nonviolent protests or boycotts, it can lead to policy changes.

In the United States, 3.5% of the population translates to nearly 12 million people. The “No Kings” movement would need to nearly double in size from its October 2025 levels to reach this threshold.

Boycotts could help reach this tipping point.

How boycotts work

Economic boycotts have a long history as a tool of collective protest as people withdraw their labor, purchases or cooperation to pressure powerful institutions.

Boycotts are a form of mass noncooperation that enables more people to resist without taking time off from work, engaging in confrontation or risking arrest. While demonstrations signal dissent, boycotts change incentives for business leaders. When boycotts cause companies to lose customers and profits slump, they can become unexpected allies in public opposition.

For example, after mass protests against federal immigration raids in Minneapolis, many of the biggest corporations operating in the state released an announcement that called on the government to de-escalate to reduce tensions in the area.

Public support for boycotts

Several consumer boycotts are underway in the U.S., with many taking aim at the Trump administration’s policies.

Boycott leaders focus on major companies, such as Target, Walmart, Amazon and Home Depot, that have donated to the White House ballroom construction project and other causes Trump is personally spearheading,

People’s Union USA, a movement seeking to leverage the power of U.S. consumers, organized what it called a nationwide “economic blackout” on Feb. 28. The organizers urged Americans to avoid spending any money for 24 hours to protest corporate influence over U.S. policies. It’s unclear how effective that boycott was.

Where corporate boycotts have worked

In the 1980s, consumer boycotts of white-owned businesses in South Africa reduced profits and drew global attention to the government’s support of apartheid, a discriminatory system that denied rights to the country’s Black majority. As business suffered, white business leaders pressed for reforms, contributing to the end of apartheid and South Africa’s multiracial elections in 1994.

In the U.S., different boycotts from both the right and the left have compelled Target to change its policies in recent years. Right-wing boycotts demanding the removal of LGBTQ+ Pride merchandise in 2023 caused Target to curtail its embrace of diversity practices.

After Trump’s 2025 executive order banning diversity, equity and inclusion programs, Target faced left-wing boycotts for ending its Racial Equity Action and Change program. The company’s sales fell and its stock declined by 33% in the first three quarters of 2025.

In March 2026, boycott leaders declared victory, saying that the boycotts led to Target’s weak financial performance.

Following the growing wave of consumer boycotts, several media companies have also faced pressure from the public.

In September 2025, Disney suspended late night talk show host Jimmy Kimmel, whose program airs on ABC, after Kimmel suggested that right-wing influencer Charlie Kirk was killed by a fellow conservative. The comedian accused Trump supporters of using his death to “score political points.” Disney owns ABC.

Kimmel’s suspension triggered a rapid public backlash. Three million viewers called for a Disney boycott to disrupt the company’s streaming revenue. Facing mounting risks to its reputation and bottom line, Disney reversed course and put Kimmel back on the air. In December 2025, it renewed his contract for the following year.

The episode illustrated how organized consumer pressure can counter attempts at political intimidation when boycott campaigns focus on a company’s core economic interests.

Uncoordinated boycotts can fail

To be sure, many boycotts fail to meet their goals even when they do succeed at raising awareness.

Their economic impact depends on how many people take part, sustained participation, and clear demands. Boycotts lacking adequate coordination and clear aims are likely to fail, especially when different groups target different companies.

The No Kings protests will no doubt continue to reflect mounting public frustration. But to be effective at their goal of reining in many of Trump’s policies and actions, we believe that this vast movement will likely require a larger, focused boycott that can hurt the revenue and reputation of companies that have financially backed the president or provided support for his policies.

The Conversation

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their academic appointment.

ref. Millions are protesting – but boycotts might be key to changing government policies – https://theconversation.com/millions-are-protesting-but-boycotts-might-be-key-to-changing-government-policies-276256

Protests coupled with boycotts tend to be most effective at making governments change policies

Source: The Conversation – USA (2) – By Lisa Schirch, Professor of the Practice of Peace Studies, University of Notre Dame

The ‘No Kings’ protests have drawn millions of Americans and may grow even larger. Frederic J. Brown/AFP via Getty Images

The organizers of the estimated 3,000 “No Kings” protests, rallies and other events planned for March 28, 2026, say they expect that the protests will be the largest such mass mobilization in U.S. history.

As scholars of peace studies and social movements, we investigate how ordinary people press their governments to change their policies.

An estimated 7 million Americans took part in the 2,100 “No Kings” protests on Oct. 18, 2025, breaking all previous records. But research that we and other scholars have conducted indicates that massive turnouts at protests may not be enough to achieve the goals of a protest movement, such as bringing about changes in government policies.

We believe that protest movements can be more effective when they place more emphasis on boycotts of corporations that support a government’s agenda than on increasing the size and scope of these protests.

That’s because history suggests that boycotts are uniquely suited to expand public participation and reach the scale necessary for political change. Boycotts attract first-time activists with simple “buy this, not that” instructions. They offer easy ways for people to feel heard with little investment of time, money or risk.

Rise of the ‘No Kings’ movement

The “No Kings” movement has been holding nonviolent protests across the U.S. since June 2025 to express mass opposition to the Trump administration’s policies.

Its organizers include a range of nonprofits. They include those supporting civil rights, such as the American Civil Liberties Union; LGBTQ+ rights, like the Human Rights Campaign; progressive political groups, including Indivisible and MoveOn; and unions, such as the American Federation of Teachers.

The protests’ organizers are harnessing growing public opposition to President Donald Trump’s second administration. Gallup’s final presidential poll, for example, conducted in December 2025, found that only about 1 in 3 Americans approved of his performance.

In March 2026, Fox News found that 6 in 10 Americans disapprove of Trump’s immigration enforcement effort, and a CBS poll found that 6 in 10 oppose the U.S. war with Iran.

The “No Kings” movement from the start has objected to harsh federal immigration enforcement tactics, including the rapid growth in the number of immigrants being detained and deported. The March 28 protests will also make the widespread opposition to the costly Iran war more visible.

“No Kings” organizers cite other reasons for their protests, such as the White House’s threats to intervene in elections, health care spending cuts and the cessation of many environmental protections.

Four protesters, some in costumes, stand next to a huge American flag.
Many of the ‘No Kings’ events on Oct. 18, 2025, took place in small towns, like Shelburne, Vt., pictured here.
Robert Nickelsberg/Getty Images

Opposition to Trump is spreading

The “No Kings” protests have spread to more parts of the United States than ever before.

Protests have taken place in every state – in large cities like Dallas, Philadelphia and Phoenix, as well as thousands of smaller towns like Corydon, Indiana, and Hamilton, Montana. The protests even drew thousands of people in some GOP strongholds.

Researchers find that only a small part of the population needs to protest, boycott or strike to create strong pressure. If 3.5% of a population participates in nonviolent protests or boycotts, it can lead to policy changes.

In the United States, 3.5% of the population translates to nearly 12 million people. The “No Kings” movement would need to nearly double in size from its October 2025 levels to reach this threshold.

Boycotts could help reach this tipping point.

How boycotts work

Economic boycotts have a long history as a tool of collective protest as people withdraw their labor, purchases or cooperation to pressure powerful institutions.

Boycotts are a form of mass noncooperation that enables more people to resist without taking time off from work, engaging in confrontation or risking arrest. While demonstrations signal dissent, boycotts change incentives for business leaders. When boycotts cause companies to lose customers and profits slump, they can become unexpected allies in public opposition.

For example, after mass protests against federal immigration raids in Minneapolis, many of the biggest corporations operating in the state released an announcement that called on the government to de-escalate to reduce tensions in the area.

Public support for boycotts

Several consumer boycotts are underway in the U.S., with many taking aim at the Trump administration’s policies.

Boycott leaders focus on major companies, such as Target, Walmart, Amazon and Home Depot, that have donated to the White House ballroom construction project and other causes Trump is personally spearheading,

People’s Union USA, a movement seeking to leverage the power of U.S. consumers, organized what it called a nationwide “economic blackout” on Feb. 28. The organizers urged Americans to avoid spending any money for 24 hours to protest corporate influence over U.S. policies. It’s unclear how effective that boycott was.

Where corporate boycotts have worked

In the 1980s, consumer boycotts of white-owned businesses in South Africa reduced profits and drew global attention to the government’s support of apartheid, a discriminatory system that denied rights to the country’s Black majority. As business suffered, white business leaders pressed for reforms, contributing to the end of apartheid and South Africa’s multiracial elections in 1994.

In the U.S., different boycotts from both the right and the left have compelled Target to change its policies in recent years. Right-wing boycotts demanding the removal of LGBTQ+ Pride merchandise in 2023 caused Target to curtail its embrace of diversity practices.

After Trump’s 2025 executive order banning diversity, equity and inclusion programs, Target faced left-wing boycotts for ending its Racial Equity Action and Change program. The company’s sales fell and its stock declined by 33% in the first three quarters of 2025.

In March 2026, boycott leaders declared victory, saying that the boycotts led to Target’s weak financial performance.

Following the growing wave of consumer boycotts, several media companies have also faced pressure from the public.

In September 2025, Disney suspended late night talk show host Jimmy Kimmel, whose program airs on ABC, after Kimmel suggested that right-wing influencer Charlie Kirk was killed by a fellow conservative. The comedian accused Trump supporters of using his death to “score political points.” Disney owns ABC.

Kimmel’s suspension triggered a rapid public backlash. Three million viewers called for a Disney boycott to disrupt the company’s streaming revenue. Facing mounting risks to its reputation and bottom line, Disney reversed course and put Kimmel back on the air. In December 2025, it renewed his contract for the following year.

The episode illustrated how organized consumer pressure can counter attempts at political intimidation when boycott campaigns focus on a company’s core economic interests.

Uncoordinated boycotts can fail

To be sure, many boycotts fail to meet their goals even when they do succeed at raising awareness.

Their economic impact depends on how many people take part, sustained participation, and clear demands. Boycotts lacking adequate coordination and clear aims are likely to fail, especially when different groups target different companies.

The “No Kings: protests will no doubt continue to reflect mounting public frustration. But to be effective at their goal of reining in many of Trump’s policies and actions, we believe that this vast movement will likely require a larger, focused boycott that can hurt the revenue and reputation of companies that have financially backed the president or provided support for his policies.

The Conversation

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their academic appointment.

ref. Protests coupled with boycotts tend to be most effective at making governments change policies – https://theconversation.com/protests-coupled-with-boycotts-tend-to-be-most-effective-at-making-governments-change-policies-276256

Why do basketball players miss shots they’ve made a thousand times before? Neuroscience has an answer

Source: The Conversation – USA – By David Van den Heever, Associate Professor of Agricultural and Biological Engineering, Mississippi State University

Every March Madness it happens. A player steps to the line, takes the shot and misses. And just like that, there goes your perfect bracket.

These are elite players. The player has made that shot thousands of times before. So what went wrong this time?

Research from my lab has found that the difference between making and missing a shot may come down to stability not only in how you move but how you think.

Measuring brain activity

My team wanted to understand how people build their skill at shooting hoops. So we examined the early phase of learning this particular skill – when coordination between your brain and body is still being formed rather than taken for granted.

Decades of research on the performance of elite athletes suggest that their sport-specific movements are consistent and their brains appear to be optimized for the task. In other words, they show less unnecessary brain activity and more focused processing on executing a specific activity. But it is not known whether these brain states are exclusive to elite performance or whether they can begin early in the learning process.

To investigate this question, my team recorded both the body movement and brain activity of novice and intermediate basketball players as they shot hoops. Specifically, we used motion capture technology to analyze their movement mechanics and electroencephalography to analyze their neural activity. After a brief practice and familiarization phase, each player took 50 shots. We then compared the shots that went in with those that did not.

What we found was telling.

Sumayah Sugapong holding basketball on the court, eyes on the off-screen basket as she prepares for a free throw
Successful shots are linked to stability and consistency in mind and body.
AP Photo/Ronda Churchill

Successful shots for all players were associated with more consistent movement patterns. The feet and lower body were positioned to provide a stable base of support, improving balance and enabling more effective transfer of force to the ball. Joint motion across the body was more coordinated, and variability was reduced in key segments of the movement, particularly at the wrist and elbow.

At the neural level, successful shots were associated with more stable neural activity. There was also increased activity related to the integration of sensory information and motor control.

Unsuccessful shots, by contrast, were much more inconsistent, showing small fluctuations throughout the movement. This suggests the players were continuously correcting their movements mid-execution. Similarly, brain activity during missed shots appeared to reflect a system still trying to figure things out, continuously evaluating, adjusting and correcting.

This trial-by-trial variability and adjustment is exactly what’s expected in early skill acquisition. According to a classic model of learning, beginners rely more heavily on effortful processing of verbal, visual and spatial information as they learn to coordinate perception and action. In other words, they are consciously and actively thinking through the movement. Learning requires exploration, error detection and correction as the brain and body are searching for a solution.

Even within this messy process of learning, successful attempts already showed signs of greater control. Making a shot was not simply about whether the brain was more or less active, but about how consistently it operated. Successful shots were marked by a more stable, less variable brain state, along with activity patterns suggesting the brain was better tuned to the demands of the task.

Mind over matter

But here’s the catch: The processes that help you learn can hurt you when you perform.

Elite athletes are not consciously micromanaging each action. Rather, they rely on systems that have been finely tuned through repetition. As skill develops, performance becomes less about effort and more about consistency. Variability decreases as neural processing becomes more efficient.

Under pressure, however, that stability is exactly what can break down. A college player may be very talented, but they are still developing physically and mentally. In high-stakes, high-pressure moments – especially like those in March Madness, which they haven’t experienced in practice – pressure can push the athlete back into their own heads. They may begin to monitor and control their movements more consciously and explicitly. This reintroduction of conscious processing can disrupt the automatic coordination they have built through practice, inadvertently increasing the variability of their movements and thoughts and therefore reducing performance.

Kiki Rice making a shot in the air as other Oklahoma State and UCLA basketball players surround her, 'MARCH MADNESS' scrolling across the jumbotron
Making a shot during competition is not quite the same as making a shot during practice.
AP Photo/Jessie Alcheh

Training that focuses not only on the mechanics of the sport but also the mental side of performance could help athletes enter, maintain or return to the mental state that supports consistent performance, even under pressure. My lab is investigating biofeedback and neurofeedback tools to help make these invisible states and metrics visible to aid in training. If athletes can learn how their brains and bodies react under pressure and practice returning to a more stable state, that may be one path toward more consistent performance.

The goal is not just to learn the right movement, but also to learn when and how to stop trying to control it.

The Conversation

David Van den Heever does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

ref. Why do basketball players miss shots they’ve made a thousand times before? Neuroscience has an answer – https://theconversation.com/why-do-basketball-players-miss-shots-theyve-made-a-thousand-times-before-neuroscience-has-an-answer-279040

NASA’s Artemis II mission will take an astronaut crew around the Moon – a space policy expert describes the long road to launch

Source: The Conversation – USA – By Scott Pace, Professor of the Practice of International Affairs, George Washington University

NASA’s Space Launch System rocket will launch a crewed capsule into orbit and then on a mission around the Moon. AP Photo/John Raoux

NASA is once again shooting for the Moon, for the first time since the 1970s. As soon as April 2026, NASA will launch its Artemis II mission, using the Space Launch System heavy lift rocket to send a crewed spacecraft, called Orion, into orbit. From there, the crew will journey to and circle around the Moon over 10 days.

In this episode of The Conversation Weekly podcast, we spoke to Scott Pace, the director of the Space Policy Institute at George Washington University. Pace worked with the George W. Bush administration in space policy, and from 2017 served for four years as the executive secretary of the National Space Council during Donald Trump’s first term as president.

In the first paragraph, it makes it sound like the spacecraft is landing on the moon. “From there, the crew to orbit around the Moon over 10 days”

Four astronauts in orange space suits with their helmets off.
The crew members of the Artemis II mission are, counterclockwise from left NASA astronauts Christina Hammock Koch, Reid Wiseman and Victor Glover and Canadian Space Agency astronaut Jeremy Hansen.
NASA

We’re about to send humans in orbit around the Moon again. What’s had to happen to get to this point?

Pace: Let’s go back to the 1980s and 1990s. After the space shuttle Challenger accident, a lot of people were thinking, “What do we do next?”

The space shuttle program was not an economic success. The recurring cost per flight was very expensive. So there was a lot of thinking about different vehicles that could be the shuttles’ successor. NASA pursued some of the higher-risk options, thinking that if they didn’t work out, they could still extend and use the shuttle. Some of those higher-risk ideas were things like single-stage-to-orbit space planes. When they didn’t work, it was OK because NASA was still working on the shuttle.

And then we had the 2003 space shuttle Columbia accident. NASA figured they could either stop for a decade or so and then try to restart a human spaceflight program once they had better technology, or try to transition the infrastructure and industrial base they had with the space shuttle to a new system.

When the second shuttle accident happened, we examined what we had to build a new system with, and we had solid rocket boosters and external tanks. To make something safer, we needed to build crew capsules. A capsule with an escape system onboard was one of the few immediate ways you could increase the likelihood of a crew’s survival.

If your eventual goal is Mars, you’ll then need a really heavy-lift vehicle to launch more crew and a heavier load. All that deliberation led to the current Space Launch System and the Orion capsule.

Four astronauts will be sent on a 10-day mission orbiting the Moon. What’s exciting to you about this mission, and what will you be looking out for?

Pace: The first thing is the performance of the solid rocket boosters on launch. Boosters are very reliable, but if they go bad, they go bad pretty quickly. The next thing is a checkpoint in Earth’s orbit when they’re going to make a decision about whether to do a translunar injection. During the translunar injection, they fire the engine to escape Earth’s orbit and get on the right path to orbit around the Moon.

Before they decide, they’re going to check the environmental control and life support system to make sure the passengers are safe and healthy inside the vehicle. Once you make the commitment to head for the Moon, that life support system is going to be essential. And they haven’t yet done a full flight test on Orion of the environmental control and life support system.

The translunar injection is actually fairly straightforward. In many ways, this is less risky than Apollo 8, which went to the Moon and then fired its engines to get into a stable orbit around the Moon. Then, it fired the engines again to come home.

Artemis II is more like Apollo 13. They’re going up, looping around the Moon and using its gravity to whip around and then come back. In some ways, it’s a less risky trajectory than Apollo 8 because you don’t have to fire the engines as much.

When the crew vehicle comes back, we’re going to look at its heat shield performance. The heat shield has had a long and complicated history. It looks like it’ll be safe, but this is a flight test. And so we’re going to look at how it reenters the atmosphere and how it handles the heat load put on it.

The SLS does come with challenges. One is the high cost. Every time you build one of these vehicles, it costs several billion dollars. The other problem is flight rate.

A conical spacecraft with the NASA worm logo in space, with Earth and the Moon shown in the background.
NASA’s Orion spacecraft had a view of both Earth and the Moon during the Artemis I mission.
NASA via AP

Some people will argue that beating China to the Moon is really important. Does that matter to you?

Pace: It matters to me if China is the only one showing up and they drive all the standards and the operating norms on the Moon. But the issue of beating China back in the near term doesn’t quite seize me as much as the longer term.

This is part of the problem I have with the term “race.” The U.S. had a space race in the past, but what we have now with China is a long-term competition.

Space is not yet contentious in the way the South China Sea is, or border disputes with India are. But I can see why some people are worried by looking at China’s behavior in other areas.

Part of the stated goal for Artemis is to secure a lasting presence on the lunar surface. Do you think there’s a rationale for nations to stay permanently on the Moon now?

Pace: Humanity’s future in space depends on two sub-questions. First: Can you live off the land and use local resources, or are you always dependent upon Earth? Second: How are you paying? Are you also financially dependent upon Earth – for example, supported by taxpayers?

If you can both use local resources and do something economically useful, then you can build space settlements and get permanent human activity beyond the Earth.

If the answer is no on both counts, then space is like Mount Everest: It’s a place of adventure and symbolism. People can go there and take pictures. But nobody really lives there.

If you can do something useful in space and generate an economic return, but still have to come home to Earth because the environment can’t support life long term, then space is like a North Sea oil platform. It’s a dangerous and difficult place, but a place where you can go for economic reasons.

If you still have to depend on taxpayer money, space may be similar to Antarctica – like going to McMurdo Station. You can do science there and have a human presence, but it’s a constrained environment.

Part of the purpose of exploration is to find out which of these futures is feasible. Some people have faith that space settlements are possible. But we really don’t know.

If it turns out there are economically useful things to do on the Moon, there may be an eventual transition. Activity on the Moon would go from a government-led effort to one led by private sector activities, including mining helium-3 or shipping water back to refueling stations.

If it turns out that none of that really makes sense, we’d still have some science presence there, but we would press on to Mars. I think there’ll be some sort of scientific presence regardless – but its size will depend on economics and markets that we, frankly, don’t understand yet.

The world today in space is much more globalized, much more democratized. Many more countries and entities are involved in space. While the U.S. wants to be the leader in this effort, it knows that simply doing it with a NASA logo is really not sufficient. The Artemis program is meant as an international and commercial partnership effort with others to voluntarily shape what space looks like.

The Conversation

Scott Pace is an advisor for Sierra Space and is a member of the Board of Trustees for the Planetary Science Institute, and the Board of Advisors for the National Security Space Association. He was a political appointee in the Administrations of George W. Bush (2002-2008) and Donald J. Trump (2017-2020). He is the Director of the Space Policy Institute at the Elliott School of International Affairs, at George Washington University, Washington, D.C.

ref. NASA’s Artemis II mission will take an astronaut crew around the Moon – a space policy expert describes the long road to launch – https://theconversation.com/nasas-artemis-ii-mission-will-take-an-astronaut-crew-around-the-moon-a-space-policy-expert-describes-the-long-road-to-launch-274481

Scientists may be overestimating the amount of microplastics in the environment – and the culprit is lab gloves

Source: The Conversation – USA – By Anne McNeil, Professor of Chemistry and Macromolecular Science and Engineering, University of Michigan

Gloves used in the laboratory that led to microplastic overestimation. Madeline Clough

It seems like every day a new study finds tiny plastic particles called microplastics where they should not be: in our bodies and our food, water and air.

Yet finding and identifying microplastics is extremely challenging, especially given their small size. One microplastic can range from as large as a ladybug to as small as an eighth of a red blood cell.

In addition, it can be hard for researchers to avoid unintentionally contaminating their samples, because these plastics are practically everywhere. As a result, much of this research may be overestimating the number of microplastics.

In a new study published in March 2026, our team found that, even when following established protocols, using certain methods to measure environmental microplastics can potentially contaminate the results.

Microplastics are tiny plastics shed from plastic waste. They are found in the environment, waterways and even the human body.

The study

We are chemists at the University of Michigan working in a collaborative team. We set out to understand how many microplastics Michiganders were inhaling when outside, and whether that depended on where they lived.

When preparing our samples, we followed all the standard protocols while conducting our research – we avoided plastic use in the lab, wore nonplastic clothing and even used a specialized chamber to reduce potential contamination from the laboratory air.

Despite these precautions, we found plastic counts in the air that were over 1,000 times greater than previous reports. We knew these numbers didn’t seem right, so what happened?

The culprit: Lab gloves

After a long path to pinpointing the contamination source, we found that laboratory gloves, which the scientific community recommends using as a best practice, can transfer particles to the surface of our samples – in this case, small metal sheets used to collect material depositing from the air. Moreover, the particles led to an overestimation of microplastic abundance in our study.

Here’s how: The particles, which we identified as stearate salts, are used to help the gloves cleanly release from their mold during the manufacturing process. When gloves are used to handle laboratory equipment, the particles are transferred to anything they touch. Stearate salts are similar to soap molecules – if you eat a lot of them, they’re probably not good for you, but they’re not harmful in the environment in the same way that microplastics are.

While not microplastics themselves, stearate salts are structurally similar to polyethylene, the type of plastic most often found in the environment. This structural similarity makes it difficult to distinguish them using the most common tools scientists use to determine whether a particle is plastic.

Researchers use vibrational spectroscopy to identify microplastics, which entails measuring how the particle interacts with light to produce what scientists call a chemical fingerprint.

Because polyethylene and stearate salts have very similar structures, they also interact with light in a similar way.

As a result, at least some of the time, the particles from gloves are incorrectly identified as microplastics. As more researchers rely on automated methods to speed up their analyses, glove residue may be increasingly mistaken for microplastics, leading to higher reports of microplastics in the environment than in reality.

How widespread is this contamination?

To investigate how prevalent this contamination might be, we looked at different glove types. We mimicked the touch between seven types of gloves while handling laboratory equipment and counted the number of microplastics we would incorrectly attribute to the environment if we followed the most common approaches.

We found that gloves can contribute over 7,000 particles per square millimeter that are misidentified as microplastics. This finding means that researchers could be unknowingly overestimating microplastic abundance in the environment when handling their samples with gloves.

Even more concerning, we found that the particles were largely less than 5 um in size. Microplastics in this size range have larger impacts on human and ecosystem health because they can more easily enter cells. By inflating microplastic counts in this size range, using laboratory gloves may jeopardize the studies that inform future policies and regulations.

A diagram showing particles coming off gloves from contact, where it causes a signal similar to a microplastic during scientific analysis.
How handling samples with gloved hands leads to an overestimation of plastics.
Madeline Clough

Moving forward

To avoid contamination, we suggest scientists avoid glove use while conducting microplastic research. If that is not possible – for example, with biological samples where the researchers must wear gloves to protect themselves – we recommend a glove made without stearates, such as those designed for electronics manufacturing. To recover older, potentially contaminated datasets, we have developed methods to help differentiate the chemical fingerprints.

Science is an iterative process. New areas of research, including environmental microplastics, introduce new challenges to the scientific community. In addressing these new challenges, we will encounter setbacks, such as unforeseen contamination.

While we had to discard our initial dataset, we expect the lessons we learned about glove contamination to reach other scientists. In addition, we plan to continue our research on Michigan’s atmospheric microplastic contamination – but this time without gloves.

It’s important to note that even if the microplastic abundance in the environment is lower than researchers originally thought, any amount of microplastics can be troublesome, given their negative effects on human health and ecosystems.

The Conversation

Anne McNeil receives funding from the National Science Foundation, the Department of Energy, the Vinyl Institute, the University of Michigan, and the State of Michigan Economic Development Corporation.

Madeline Clough receives funding from the University of Michigan Rackham Graduate School and the University of Michigan College of Literature, Science, and The Arts. She is affiliated with the Michigan Microplastics Coalition.

ref. Scientists may be overestimating the amount of microplastics in the environment – and the culprit is lab gloves – https://theconversation.com/scientists-may-be-overestimating-the-amount-of-microplastics-in-the-environment-and-the-culprit-is-lab-gloves-258545

Vagus nerve stimulation shows promise as a way to counter Alzheimer’s disease- and age-related memory loss

Source: The Conversation – USA – By Elizabeth Riley, Lecturer in Psychology, Cornell University

The vagus nerve, which carries information between the brain and heart, lungs and other organs, might regulate the activity of a tiny brain region called the locus coeruleus. Sebastian Kaulitzki/Science Photo Library via Getty Images

Most people think of Alzheimer’s disease as an illness of aging. But in fact, the brain changes that characterize it begin much earlier – sometime around the third decade of life.

In the earliest of these changes, a tangled version of a protein called tau starts building up in a tiny region deep in the brain involved in sleep, attention and alertness, called the locus coeruleus. Tau later spreads to the rest of the brain.

Developing tau tangles doesn’t mean a person has Alzheimer’s disease – in fact, it happens to nearly everyone to varying degrees. But because these changes start in the locus coeruleus, some brain researchers – myself included – see this area as a canary in the coal mine for developing Alzheimer’s disease

We are exploring whether stopping or slowing down tau tangles in this brain region, or otherwise maintaining its health, may be a way to interrupt how the disease ultimately unfolds and to prevent other aspects of cognitive aging.

Emerging research from my lab and others is investigating the idea that a therapy called vagus nerve stimulation, which is already widely used for other health conditions, could be one way of keeping the locus coeruleus functioning properly.

The locus coeruleus and Alzheimer’s disease

The locus coeruleus sits in the brain stem, the lowest part of the brain. Its name, “blue spot,” comes from a pigment called neuromelanin that its cells produce.

The locus coeruleus plays a crucial role in multiple aspects of basic human functioning. It makes virtually all of the brain’s norepinephrine, a chemical critical for sleep, alertness, focus, learning and even immune function. And it receives inputs from nerves originating throughout the brain and body – including from the vagus nerve, which carries information to and from the heart, lungs and other organs.

My research explores this brain region’s structure, how nerve cells pass messages within it and how it connects with other brain regions. I also investigate how those features change throughout life and affect thinking and memory.

Alzheimer’s disease destroys memory and thinking skills, but researchers don’t yet understand how or why.

Studies suggest that starting in middle age, nerve cells in the locus coeruleus may get damaged by tau buildup, and that damage may correlate with declines in memory. Tau buildup, cell death and loss of function in the locus coeruleus precedes and predicts Alzheimer’s diagnosis and symptoms.

This has led researchers to hypothesize that keeping the locus coeruleus healthy could be a way to protect the rest of the brain, too.

Vagus nerve stimulation and brain health

The vagus nerve carries information between the brain and organs in the chest and abdomen, such as the heart and intestines, helping the brain monitor and regulate many of the body’s essential organs. It is responsible for sending rest and digest messages throughout the brain and body, stimulating digestion and promoting cellular repair.

In the 1980s and 1990s, researchers discovered that stimulating the vagus nerve can help ease epilepsy. They also found that doing so often also had other benefits, such as improving mood and thinking.

Today, vagus nerve stimulation is approved by the Food and Drug Administration not just for treating epilepsy, but also for migraine and depression, as well as to aid with stroke rehabilitation.

Vagus nerve stimulation for epilepsy and depression generally involves implanting an electrical stimulator in the left side of a patient’s chest, where the vagus nerve passes. Noninvasive devices for treating headaches deliver gentle pulses of electricity to certain places on the neck or ear where the vagus nerve is very close to the surface of the skin.

Even before the discovery of locus coeruleus’s link to Alzheimer’s disease, researchers hypothesized that vagus nerve stimulation might help mood and thinking in people with the condition. That’s because vagus nerve stimulation might work in part by raising brain levels of norepinephrine – and people with Alzheimer’s have too little norepinephrine in their brains.

Keeping the pace

Neuroscientists still don’t know exactly how or why vagus nerve stimulation might be beneficial for the brain, but one leading theory is that it helps regulate the activity of nerve cells in the locus coeruleus, enabling it to function properly.

Too much locus coeruleus activity could potentially make people too alert, causing them to feel stressed or even panicked. In fact, a hyperactive locus coeruleus fuels some symptoms of post-traumatic stress disorder. Conversely, too little could cause depression or memory problems.

A scan of the brain with the locus coeruleus lit up in the brain stem
The locus coeruleus, which means ‘blue spot,’ is located in the brain stem, the lowest part of the brain.
Elizabeth Riley, CC BY-SA

Some forms of vagus nerve stimulation neither turn up nor turn down locus coeruleus activity. Instead, they seem to affect the timing and pace of firing in its neurons. Other forms of vagus nerve stimulation seem to increase norepinephrine in the brains of rats, and researchers hypothesize that this may also be how vagus nerve stimulation treats epilepsy.

These different findings have led researchers to suggest that vagus nerve stimulation could act as an effective regulator for the locus coeruleus, enabling it to establish just the right level of activity for optimal functioning.

Can vagus nerve stimulation counter memory loss?

Intriguing hints are emerging that vagus nerve stimulation may help the aging brain.

A handful of studies have found that vagus nerve stimulation can prevent memory from worsening, or even improve it, in people with mild cognitive impairment or in the early stages of Alzheimer’s disease. One trial of 52 people ages 55 to 75 who were diagnosed with mild cognitive impairment reported meaningful improvements in memory and overall cognition after getting vagus nerve stimulation for an hour per day, five days a week for about six months.

Research in healthy adults around age 60 – and in healthy adults age 18 to 25 – has even reported improvements in different aspects of memory after just one session of vagus nerve stimulation.

This work is still very preliminary, but it offers hope for a new way of keeping some of the distressing symptoms of Alzheimer’s disease and aging at bay.

The Conversation

Elizabeth Riley receives funding from the National Institute on Aging.

ref. Vagus nerve stimulation shows promise as a way to counter Alzheimer’s disease- and age-related memory loss – https://theconversation.com/vagus-nerve-stimulation-shows-promise-as-a-way-to-counter-alzheimers-disease-and-age-related-memory-loss-269465