Cancer vaccines could transform treatment and prevention – but misinformation about mRNA vaccines threatens their potential

Source: The Conversation – USA (3) – By Dannell D. Boatman, Assistant Professor and Health Communication Researcher, West Virginia University

A cancer vaccine would only help patients if they were willing to take it. Javier Zayas Photography/Moment via Getty Images

Scientists are making rapid progress toward a long-awaited goal that could help to reshape cancer care: mRNA cancer vaccines with the potential to significantly boost the immune system’s ability to fight and eliminate tumors.

Since the early 2000s, there have been over 120 promising clinical trials testing the use of mRNA vaccines to treat multiple cancer types, such as melanoma, brain, breast, lung and prostate cancer.

At the same time, misinformation about so-called turbo cancer began spreading widely on social media, with mainstream media outlets first reporting on it in late 2022. Turbo cancer refers to the false claim that COVID-19 mRNA vaccines cause unusually aggressive cancers.

As a researcher in health communication who monitors cancer-related conversations online, I have seen how quickly new misinformation can spread and the impact it can have on people’s health decisions. In the case of mRNA cancer vaccines, this false narrative could undermine public confidence in an important tool that may help prevent or treat cancer in the future.

Cancer research and mRNA vaccines

Most people likely first heard about mRNA technology through COVID-19 vaccines, but scientists have been studying it for decades.

How mRNA vaccines work is by delivering instructions that prompt the body’s cells to make specific proteins. This process teaches the immune system how to recognize and attack those proteins. In cancer research, scientists can design highly targeted vaccines that train the immune system to find tumor cells and more effectively kill them without harming healthy cells.

Cancer vaccines teach the immune system to kill tumor cells more effectively.

One example of this potential comes from studies on glioblastoma, an aggressive brain tumor with few effective treatments. Researchers have found that a personalized mRNA vaccine can rapidly activate people’s immune systems against this type of brain cancer and improve survival.

The body of evidence that mRNA vaccines can transform how researchers harness the immune system to treat cancer is growing. However, even the most promising medical advances can only improve health if people are willing to use them.

Rise of the ‘turbo cancer’ narrative

Turbo cancer” is a term often used by anti-vaccine advocates who claim – without credible evidence – that COVID-19 mRNA vaccines are causing unusually aggressive cancers.

This inaccurate narrative has trickled into the mainstream news. In September 2025, a controversial U.K. cardiologist claimed that the COVID-19 vaccine contributed to the royal family’s recent cancer diagnoses, spurring immediate backlash from the medical community. Although uncommon, some public figures and health professionals have claimed that the vaccines could cause cancer despite ample contradictory evidence, often by misinterpreting or misrepresenting studies.

Health misinformation can be described as false or misleading health-related claims shared with the public that are not supported by scientific evidence, are based on unverified personal stories or are opinions presented as facts. For example, while tracking discussions about the HPV vaccine across social media platforms, my team and I found that safety fears, mistrust of authority and conspiracy claims were widespread online.

Vaccine misinformation accelerated during the COVID-19 pandemic, causing what researchers call an infodemic: the rapid spread of both accurate and false health information during a public health crisis. The COVID-19 infodemic made it harder for people to find trustworthy guidance and shaped public attitudes toward vaccines.

“Turbo cancer” reflects many of the same patterns and narratives as the COVID-19 infodemic.

In a social listening study, which involves systematically monitoring online conversations about different topics, my team and I observed countless posts about turbo cancer beginning in July 2023 and continuing through early 2026. Many posts rely on emotionally compelling anecdotes, misinterpretations of animal studies, misuse of adverse events reporting and recycled myths that vaccines alter human DNA. Some posts also link rising cancer rates in younger adults to the COVID-19 vaccine. However, large population studies have found no increased cancer risk following vaccination.

None of these turbo cancer claims are supported by credible evidence. But on social media, repetition, personal stories and scientific-sounding language can make misinformation appear legitimate and help it spread quickly.

Cancer vaccine misinformation harms health

At first glance, fringe claims such as turbo cancer may seem easy to dismiss. But research shows that they can have real-world consequences, and cancer-related misinformation can be particularly consequential.

Inaccurate information about cancer treatment is common online, and researchers have shown that it influences patient decisions. When patients rely on unproven approaches instead of recommended therapies, their risk of death can increase substantially.

Clinicians are already seeing the effects of misinformation in routine care. Oncologists report having to address myths or misleading information that patients have encountered, though researchers do not yet know how common these conversations are across cancer care.

Patient showing doctor their phone in exam room
Doctors are tasked with addressing misinformation that patients encounter online.
SDI Productions/E+ via Getty Images

mRNA technology is entering a pivotal phase in its development. Scientific progress is accelerating, but public understanding has not kept pace. Repeated exposure to misleading claims can erode trust in mRNA technology over time, increasing the likelihood that some patients will decline mRNA therapies in the future.

If misleading narratives such as turbo cancer continue to spread, they could complicate the future rollout of mRNA vaccines and limit their lifesaving benefits.

Keeping communication in pace with science

Once misinformation takes hold of public understanding, changing its course can be difficult.

Research has consistently shown that proactive, transparent and persuasive communication can counter misinformation. It also shows that trust, once lost, is difficult to rebuild.

Medical innovations can save lives, but only if communication keeps up. This means monitoring emerging misinformation trends on social media, addressing concerns early on, equipping clinicians to have effective patient conversations and designing public health messaging that builds public understanding of new medical technologies before they are widely introduced in the clinic.

Scientific innovation alone is not enough to improve health. Ensuring that the public can evaluate medical innovations like mRNA cancer vaccines based on evidence, rather than viral misinformation, is part of the scientific challenge.

The future of cancer care depends not just on scientific discovery, but on public understanding and trust.

The Conversation

Dannell D. Boatman receives funding from Merck, Sharp & Dohme LLC, the National Institutes of Health, the National Institute of General Medical Sciences and the Centers for Disease Control and Prevention.

ref. Cancer vaccines could transform treatment and prevention – but misinformation about mRNA vaccines threatens their potential – https://theconversation.com/cancer-vaccines-could-transform-treatment-and-prevention-but-misinformation-about-mrna-vaccines-threatens-their-potential-276809

My research on wheelchair basketball challenges one of the biggest assumptions about sex differences in sports

Source: The Conversation – USA (3) – By Leanne Snyder, Assistant Professor of Exercise Science, Loyola University Chicago

Physiological differences between women and men in sports may be far less pronounced in wheelchair basketball players. Steph Chambers/Staff via Getty Images Sports

Every March, millions of Americans fill out brackets and tune in to watch the NCAA college basketball tournaments known as March Madness. The men’s and women’s competitions unfold in parallel, each with their own brackets, champions, storylines and fan bases.

The separation reflects one of the most deeply embedded assumptions in sports: that women and men perform differently enough that they must compete apart.

The divide is so normal, it’s rarely explained: On average, men are faster, stronger and have more endurance. As a result, performance differences between men and women are often assumed to follow directly from these physical traits.

This notion shape how sports organizations structure competition, how coaches train athletes and how researchers study performance. Sex becomes a shortcut – a way to predict what athletes can do before they ever step onto the court.

As an exercise scientist who studies the physical demands of Paralympic sports, I wanted to know whether this assumption actually holds up.

My research on elite wheelchair basketball suggests it may not. I found that many of the differences widely attributed to physiological differences between women and men in sports are far less pronounced in wheelchair basketball players – and in most cases absent altogether.

It may seem that wheelchair sports are too different from nondisabled sports to compare. But in my view, they may instead reveal what sports look like when performance is measured by what athletes can do, rather than presumptions tied to their sex.

Although international competitions of wheelchair basketball have separate women’s and men’s teams, athletes at the national level often train together.

Testing different abilities

In most sports, presumptions about physical differences between the sexes appear early, often starting with elementary school physical education classes and youth teams.

Wheelchair basketball works differently. Although international competitions have separate women’s and men’s teams, athletes at the national level often train together, while women sometimes compete in men’s leagues and vice versa.

As part of my Ph.D. research, I examined how elite wheelchair basketball players move during competition by asking athletes from the Australian national men’s and women’s teams to wear movement sensors during five international-level games in 2022.

The sensors recorded how often players accelerated and decelerated, how frequently they changed direction, how fast they moved and how much distance they covered. Accelerations, decelerations and changes of direction are typically the most physically demanding movements in wheelchair basketball. To ensure fair comparisons, I adjusted all measures for playing time.

A consistent difference emerged. Players with less severe impairments – those with greater trunk control and stability – performed more high-intensity actions than players with more severe impairments. Female athletes with less severe impairments accelerated and decelerated more frequently and reached higher peak speeds, and male athletes showed the same pattern.

When I compared performance by sex, however, the differences were much less pronounced. Across most measures – including distance covered, average speed and high-intensity movements – female and male athletes performed similarly over the course of multiple games.

Performance beyond sex

If sex-based performance differences are so common in sports, why didn’t they appear in my research? The answer lies partly in how wheelchair basketball is organized.

To compete, athletes are assigned a classification based on how their impairment affects movement during play. These classifications range from 1.0 to 4.5, with lower numbers indicating more severe impairments. The system is designed to account for athletes with wide variations in physical disabilities, particularly differences in trunk control, balance and the ability to generate force and change direction in their game wheelchairs.

During games, teams must stay under a combined classification limit of 14 points for the five players on court. This means lineups are built around functional movement ability rather than sex, balancing players with different movement capacities within lineups so that no single team gains an unfair advantage.

Shelley Cronau, a player on Australia's Paralympics wheelchair basketball team, grabs a loose ball in a match against Japan in the Tokyo 2020 Paralympic Games.
Wheelchair basketball uses a system of classifications to balance the wide variations in athletes’ disabilities.
Carmen Mandato/Staff via Getty Images Sports

With this in mind, it makes sense that classification, not sex, explained the differences I observed. In other words, wheelchair basketball is designed around physical variation in sports – not just between women and men, but across individuals with very different movement capacities and roles on the court. In this context, sex becomes one variable among many, rather than the primary basis for performance.

This pattern isn’t unique to wheelchair basketball. In wheelchair rugby, where women and men compete together on the same international teams, research has also found that game demands are shaped more by players’ classification and on-court roles than by sex.

Challenging sports science norms

My findings challenge a near-universal assumption in sports: that sex is the primary factor defining physical ability.

To be clear, there are contexts where sex-based comparisons matter. Differences in average muscle mass, body size and hormone profiles can influence performance in many sports, which is one reason competitions are typically separated into women’s and men’s divisions. Safety concerns are also frequently cited as a reason for maintaining separate competitions.

But when sex becomes the primary framework for understanding performance, it can obscure other important factors such as strength, body size, training history and access to coaching.

Research supports this idea. One study comparing athletes by both sex and strength found that many differences often attributed to sex were better explained by strength. Another review found little consistent evidence for sex-specific movement patterns in jumping and landing tasks, concluding that many reported differences are better explained by training exposure, motor skill or sociocultural factors than by sex alone.

Put simply, what is often labeled a sex difference may instead reflect unequal opportunities to develop physical capacity – much of which is trainable – rather than fixed, innate ability.

This perspective does not mean sex differences disappear, but it suggests that they may not always be the most informative way to understand performance. In some cases, focusing primarily on sex-based categories may even risk underselling what some young athletes are capable of.

Looking more closely at individual factors such as strength, agility, sport-specific skills and training exposure may give coaches a clearer picture of how athletes actually perform, rather than relying on long-standing presumptions about what girls and boys are capable of.

The Conversation

Leanne Snyder does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

ref. My research on wheelchair basketball challenges one of the biggest assumptions about sex differences in sports – https://theconversation.com/my-research-on-wheelchair-basketball-challenges-one-of-the-biggest-assumptions-about-sex-differences-in-sports-261624

¿Y si mi sartén contiene una sustancia eternamente tóxica?

Source: The Conversation – (in Spanish) – By Vanessa Tabernero, Profesora contratada doctora / Decana Adjunta Grado Química, Universidad de Alcalá

Anastasia Kamysheva/shutterstock

Todos sabemos qué es el teflón o, al menos, sabemos que características tiene: es ignífugo –no arde cuando cocinamos con él–, es hidrófugo –no absorbe el agua– y es resistente. Por eso, las sartenes recubiertas de teflón se presentaron hace unas décadas como la panacea en la cocina, ya que no se pegaba nada y, además, eran muy fáciles de limpiar.

Durante más de 60 años, los polímeros con cadenas de carbono perfluoradas (todos los demás sustituyentes –átomos que se encuentran unidos a una cadena hidrocarbonada– son flúor) o polifluoradas (con algunos enlaces con flúor), PFAS por sus siglas en inglés, han penetrado en todas las industrias. Se usan en la fabricación de productos como espumas contra incendios, ropa protectora, muebles, adhesivos, envases de alimentos, superficies de cocina antiadherentes resistentes al calor y aislamiento de cables eléctricos.

Entre ellos, el más conocido es el politetrafluoroetileno (PTFE), conocido como teflón por la marca que lo comercializó. Sus características responden a las especiales propiedades del enlace carbono-flúor, que es uno de los más fuertes conocidos, lo que le hace bastante inerte y difícil de degradar. De ahí que, por su durabilidad, se llamen sustancias químicas eternas.

Europa pone límites

La Unión Europea (UE) está legislando para disminuir el uso de los PFAS: las clasifica como sustancias persistentes y bioacumulativas que, además, migran en el planeta y se encuentran no solo en suelos, sino también en aguas y en el aire.

Se estima que, solo en Europa, cada año acaban en el medioambiente 75 000 toneladas de PFAS. El proyecto Forever Pollution ha calculado que hay alrededor de 23 000 sitios contaminados con PFAS en Europa y un 10 % de estos son «puntos críticos», con altos niveles de contaminación.

Por qué el tóxico el teflón

Si hemos dicho que son sustancias eternas –que no se descomponen fácilmente en la naturaleza–, ¿por qué son peligrosos? La razón es que, una vez obtenidos, los PFAS son estables, pero las sustancias químicas utilizadas para fabricar los polímeros o las emitidas a lo largo de su ciclo de vida son altamente tóxicas.

En el primer caso, tenemos como ejemplo el trifluorometano (HFC-23), que se forma como subproducto en la obtención de teflón y tiene un potencial de calentamiento global 12 400 veces mayor que el CO₂. En el segundo, podemos considerar los microplásticos que se liberan al lavar textiles que contienen PFAS, terminan en el agua de la naturaleza, provenientes de las plantas de tratamiento de aguas residuales, ya sea por las aguas de descarga o por los lodos de depuradora que a veces se esparcen sobre suelos agrícolas.

¿Qué hago con mi sartén?

¿Debo dejar de usar mis utensilios de cocina? Como este material es muy estable, las sartenes de teflón en buen estado no representan un riesgo, pero si su recubrimiento se deteriora o se expone a temperaturas superiores a 260 °C, pueden liberar partículas con residuos de PFAS.

No podemos demonizar los PFAS, ya que son materiales importantes en nuestra vida diaria. Se usan además en dispositivos médicos, de defensa y aeroespaciales, porque tienen buenas prestaciones y alta durabilidad. Pero sería mejor que buscáramos sustitutos que garanticen estas prestaciones sin afectar nuestra salud a largo plazo.

Por ejemplo, podríamos elegir sartenes de hierro o de porcelana que no tengan este antiadherente.

El problema de los acuíferos

Aparte del menaje de cocina, los niveles de PFAs en aguas están siendo cada vez más preocupantes y las directivas son escasas y muy variables. Pensemos en zonas cercanas a industrias productoras de este tipo de sustancias, pero también en aeropuertos, instalaciones militares, zonas de entrenamiento contra incendios o lugares donde se han producido incendios importantes, en los que se utiliza AFFF fluorado (una espuma contra incendios).

Estos compuestos se pueden filtrar a los acuíferos y la ingestión de agua potable contaminada es una de las principales vías por las que los seres humanos pueden estar expuestos a los PFAS.

Estados Unidos tiene ahora un límite de cuatro nanogramos por litro (ng/L) por producto fabricado con PFAS, mientras que la Directiva sobre agua potable de la UE establece que 20 PFAS muy extendidos no deben superar colectivamente los 100 ng/L.

Cáncer y disfunciones hormonales

Cada vez hay más pruebas de que algunos PFAS conllevan graves riesgos para la salud, y pueden provocar cáncer, enfermedades tiroideas y problemas de fertilidad, así como defectos en el desarrollo de los fetos.

Está en nuestras responsabilidades ciudadanas exigir a los gobiernos un mayor control sobre estas sustancias para que la normativa sea restrictiva al respecto y se garanticen sistemas como el filtrado de aguas, que permita que los niveles sean los suficientemente bajos para no producir daños.

La UE ya ha considerado los PFAS dentro de su Estrategia sostenible de productos químicos, donde se busca minimizar y sustituir a aquellos productos que están en el foco. Sin duda, los PFAS son uno de ellos.

The Conversation

Vanessa Tabernero no recibe salario, ni ejerce labores de consultoría, ni posee acciones, ni recibe financiación de ninguna compañía u organización que pueda obtener beneficio de este artículo, y ha declarado carecer de vínculos relevantes más allá del cargo académico citado.

ref. ¿Y si mi sartén contiene una sustancia eternamente tóxica? – https://theconversation.com/y-si-mi-sarten-contiene-una-sustancia-eternamente-toxica-277100

Dar una nueva vida a las neuronas para luchar contra el párkinson

Source: The Conversation – (in Spanish) – By Tania Payo Serafín, Investigadora predoctoral en Biomedicina y Ciencias de la Salud, Universidad de León

Neuronas marcadas con fluorescencia verde bajo microscopio ManuelSchottdorf / Wikimedia Commons, CC BY-SA

La enfermedad de Parkinson afecta a más de diez millones de personas en el mundo. Se trata de un trastorno neurodegenerativo en el que algunas neuronas del cerebro mueren progresivamente. Estas células afectadas se encuentran en una región llamada “sustancia negra” y tienen una función clave: producir dopamina, una molécula esencial para controlar el movimiento. Cuando estas neuronas desaparecen surgen los síntomas más conocidos como temblores, rigidez muscular, lentitud y dificultades para caminar.

Durante décadas, los tratamientos se han basado en compensar la pérdida de dopamina en el cerebro. Si bien es cierto que fármacos como la levodopa pueden mejorar notablemente los síntomas, presentan una limitación: no detienen la enfermedad ni recuperan las neuronas perdidas.

En otras palabras, se actúa sobre las consecuencias del problema (la pérdida de dopamina), pero no se arregla su origen (la muerte de neuronas). Una nueva estrategia está empezando a cambiar ese enfoque. En lugar de limitarse a compensar el daño, intenta repararlo.

¿Y si pudiésemos reemplazar las neuronas?

La terapia celular parte de un concepto sorprendentemente sencillo. Si el párkinson destruye las neuronas que producen la dopamina, ¿por qué no reemplazarlas por otras nuevas?

Durante años esta idea fue más un sueño que una posibilidad real. Las neuronas son extremadamente complejas. No basta con introducir cualquier célula en el cerebro: deben ser del tipo correcto, sobrevivir al trasplante, integrarse en los circuitos neuronales y producir dopamina de manera controlada.

El gran salto llegó con el desarrollo de las células madre pluripotentes inducidas (iPSC). Estas fueron descritas por el grupo de investigación liderado por el científico japonés Shinya Yamanaka, que recibió por ello el Premio Nobel de Fisiología o Medicina en 2012.

Las iPSC se obtienen reprogramando células adultas, como las de la piel, para devolverlas a un estado similar al embrionario. Desde ahí pueden convertirse en muchos tipos celulares, incluidas las neuronas productoras de dopamina.

Gracias a esta tecnología, la idea de reemplazar neuronas dejó de ser ciencia ficción.

Dos ensayos clínicos que marcan un antes y un después

En 2025 se publicaron en la revista Nature dos ensayos clínicos pioneros que han llevado esta estrategia al cerebro humano.

En uno de ellos los investigadores trasplantaron neuronas productoras de dopamina derivadas de células madre pluripotentes inducidas a pacientes con párkinson. El estudio mostró que el procedimiento era seguro y que las células implantadas podían sobrevivir durante largos periodos de tiempo y producir dopamina en el cerebro humano.

El segundo ensayo utilizó neuronas derivadas de células embrionarias humanas (hES). De nuevo, los resultados indicaron una buena tolerabilidad y mostraron señales de beneficio clínico duradero.

Comprobación de la producción de dopamina por parte de las neuronas trasplantadas en un paciente a los 12 y 24 meses tras la operación. Imagen traducida del estudio https://www.nature.com/articles/s41586-025-08700-0.
CC BY-NC-ND

¿Qué se ha observado en los pacientes?

Aunque todavía es pronto para sacar conclusiones definitivas, los estudios han mostrado varios resultados prometedores:

  • Las células trasplantadas sobreviven en el cerebro.

  • Producen dopamina de forma detectable.

  • Algunos pacientes presentan mejoría en sus síntomas motores.

  • No se han observado problemas graves de seguridad a corto plazo.

Esto no significa que la terapia esté lista para uso clínico general, pero sí que el enfoque es biológicamente viable.

¿Por qué este avance es tan importante?

El párkinson es una enfermedad neurodegenerativa progresiva. Con el tiempo la pérdida neuronal continúa y los tratamientos actuales se vuelven menos eficaces. La terapia celular podría ofrecer varias ventajas clave:

  1. Actuar sobre la causa del problema, no únicamente sobre sus consecuencias.

  2. Restaurar la producción natural de dopamina en lugar de administrarla de manera externa.

  3. Proporcionar beneficios duraderos, potencialmente durante años.

Pero aún no es una cura

Es importante mantener expectativas realistas: estos avances no significan que exista ya una cura disponible.

Los ensayos realizados hasta ahora incluyen pocos pacientes, y el seguimiento aún es limitado. Es necesario comprobar que las células trasplantadas sobreviven durante muchos años y que los beneficios se mantienen en el tiempo.

Además, no todos los pacientes con párkinson son iguales. La enfermedad evoluciona de forma distinta en cada persona y todavía no está claro quiénes se beneficiarán más del trasplante.

Por último, el párkinson es una enfermedad compleja que, con el tiempo, afecta a más sistemas además de las neuronas productoras de dopamina. Reemplazar estas células podría mejorar mucho los síntomas motores, pero probablemente no resolverá todos los aspectos de la enfermedad.

Un camino largo, pero prometedor

A pesar de las limitaciones, estos ensayos representan un hito histórico. Por primera vez la comunidad científica dispone de evidencia clínica de que reemplazar neuronas productoras de dopamina en humanos es factible y potencialmente beneficioso.

La terapia celular aún está en sus primeras fases, pero marca una dirección clara. La ruta consiste en avanzar desde tratamientos puramente sintomáticos hacia estrategias capaces de reparar el cerebro.

Para millones de personas que viven con la enfermedad de Parkinson este camino todavía es largo. Pero, por primera vez en décadas, la pregunta ya no es si podremos intentar reconstruir las neuronas perdidas, sino cuándo y en qué pacientes podrá hacerse de forma segura y eficaz.

The Conversation

Las personas firmantes no son asalariadas, ni consultoras, ni poseen acciones, ni reciben financiación de ninguna compañía u organización que pueda obtener beneficio de este artículo, y han declarado carecer de vínculos relevantes más allá del cargo académico citado anteriormente.

ref. Dar una nueva vida a las neuronas para luchar contra el párkinson – https://theconversation.com/dar-una-nueva-vida-a-las-neuronas-para-luchar-contra-el-parkinson-276099

Iran war shows how AI speeds up military ‘kill chains’

Source: The Conversation – UK – By Craig Jones, Senior Lecturer in Political Geography, Department of Geography, Newcastle University

The US-Israel war on Iran has been described as “the first AI war”. But recent deployments of artificial intelligence are, in fact, the latest in a long history of technological developments that prize a need for speed in the military “kill chain”.

“Sixty seconds – that’s all it took,” claimed a former Israeli Mossad agent of the strikes that killed Iran’s supreme leader, Ayatollah Ali Khamenei, on February 28 2026, the first day of the US-Israel war on Iran.

The speed and scale of war have been significantly enhanced by use of AI systems. But this need for speed brings serious risks for civilians and military combatants alike.

Modern military operations produce and rely on an enormous amount of intelligence. This includes intercepted phone calls and text messages, the mass surveillance of the internet (known as “signals intelligence”), as well as satellite imagery and video feeds from loitering drones. We can think of all this intelligence as data – and the problem is, there’s too much of it.

As early as 2010, the US Air Force was concerned about “swimming in sensors and drowning in data”. Too many hours of footage, and too many analysts manually reviewing this intelligence.

AI systems can dramatically speed up the analysis of military intelligence. Brad Cooper, head of US Central Command (CentCom), recently confirmed the use of AI tools in the war against Iran, saying:

These systems help us sift through vast amounts of data in seconds, so our leaders can cut through the noise and make smarter decisions faster than the enemy can react … Advanced AI tools can turn processes that used to take hours and sometimes even days into seconds.

In 2024, an investigation by Georgetown University found that the US Army’s 18th Airborne Corps had employed AI to assist with intelligence processing – reducing a team of 2,000 to just 20.

The allure of speed

In the second world war, the aerial targeting cycle – from collecting images to assembling target packages complete with intelligence reports – could take weeks or even months. But over the ensuing decades, the US military set about what it called “compressing the kill chain” – shortening the time between the identification of a target and use of force against it.

During the first Gulf war of 1991, Iraq’s president Saddam Hussein made use of mobile missile launchers that would roam the desert firing Scud missiles. By the time US radar identified its location, the launcher could be miles away. This “shoot and scoot” tactic required new technology to track these mobile targets.

Mobile Scud missile launchers proved a new challenge for the US military during the first Gulf war.

A key breakthrough came shortly after the September 11 attacks in the form of an armed Predator drone.

In November 2002, the CIA targeted and killed Al Qaeda’s leader in Yemen, Qaed Salim Sinan al-Harithi. This heralded a new era of warfare in which drones piloted from military bases in the US flew remotely over the skies of Yemen, Somalia, Pakistan, Iraq, Afghanistan and elsewhere.

The drones’ powerful cameras could take high-resolution video and beam it back to the US via satellite in a matter of seconds, enabling the drone operators to track mobile targets. The same drone which had eyes on the target could fire missiles to kill or destroy the target.

With greater speed comes greater risk

Two decades ago, it was easy to dismiss as hyperbole the idea that the coming age of cyberwarfare might bring about “bombing at the speed of thought”, a phrase coined by American historian Nick Cullather in 2003. Yet with the advent of AI warfare, the unthinkable has become almost antiquated.

Part of the push to employ AI tools is the sense that human thought is no match for the processing speeds enabled by AI systems. The US Department of Defense’s artificial intelligence strategy states: “Military AI is going to be a race for the foreseeable future, and therefore speed wins … We must accept that the risks of not moving fast enough outweigh the risks of imperfect alignment.”

While the precise uses of AI by US and other military is shrouded in secrecy, information has been made public that highlights the risks of its use on civilian populations.

In Gaza, according to Israeli intelligence sources, the AI systems Lavender and Gospel have been programmed to accept up to 100 civilian casualties (and occasionally even more) for a strike on a single suspected Hamas combatant. More than 75,000 people are estimated to have been killed there since October 7 2023.

In February 2024, a US airstrike killed a 20-year-old student, Abdul-Rahman al-Rawi. At the time, a senior US official admitted the strikes had used AI targeting – although confusingly, the US military now says it has “no way of knowing” whether it used AI in specific airstrikes.

The risk is that AI could lower the threshold or cost of going to war, as people play an increasingly passive role in reviewing and rubber-stamping the work of AI.

The embedding of AI into military kill chains intersects with other alarming developments. After years of inaction, the US military spent more than a decade developing an infrastructure to avoid civilian casualties in war, but it has been almost totally dismantled under the Trump administration.

The lawyers who give advice to the military on targeting operations, including compliance with international law and rules of engagement, have been sidelined and fired.

Meanwhile, since the start of the war in Iran, more than 1,200 civilians have been killed, according to the Iranian Health Ministry. On February 28, the US military struck an elementary school in the south of Iran, killing at least 175 people, most of them children.

The US secretary of defense, Pete Hegseth, has been clear that the military’s aim in Iran is for “maximum lethality, not tepid legality. Violent effect, not politically correct”.

With such an attitude, and by privileging speed over deliberation, civilian casualties become inevitable, and accountability ever more elusive.

The Conversation

Craig Jones receives funding from United Kingdom Research and Innovation (UKRI). He is author of The War Lawyers: US, Israel and Spaces of Targeting’ (Oxford University Press, 2020).

Helen M Kinsella does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

ref. Iran war shows how AI speeds up military ‘kill chains’ – https://theconversation.com/iran-war-shows-how-ai-speeds-up-military-kill-chains-278492

Can ‘mini brains’ replace lab animals? Organoids are changing how scientists study disease

Source: The Conversation – Canada – By Habib Rezanejad, Professor of cellular and molecular biology, MacEwan University

As a researcher, I still remember the discomfort I felt every time I had to sacrifice laboratory animals for an experiment. For decades, animals like mice, rats and pigs have been essential tools in biomedical research. Yet many scientists are asking whether better, more humane alternatives are possible.

Globally, it’s estimated that close to 200 million animals are used in laboratory research each year. While animal models have helped generate major medical breakthroughs, they don’t always reflect how human biology works.

An image of purple-coloured three-dimensional organoids generated from mouse pancreatic ductal epithelial cells.
Three-dimensional organoids generated from mouse pancreatic ductal epithelial cells.
(Habib Rezanejad)

New technologies are now offering scientists a promising alternative: organoids — tiny three-dimensional versions of human organs grown in the lab.

These “mini organs” are grown from human stem cells and can reproduce some of the complex cell types and interactions found in the body. Because they’re derived from human cells, organoids offer researchers a way to study human diseases more directly than traditional animal models.

Organoids for brain research

This approach is gaining huge attention in brain research. Compared with many other organs, the brain presents unique challenges for scientists.

Brain disorders are often complex and difficult to define precisely, involving subtle changes across many types of cells and neural circuits. At the same time, the brain is one of the least accessible organs in the body. Unlike blood or skin, living brain tissue cannot be easily sampled from healthy individuals.

Alzheimer’s disease, for example, is a growing global health concern, especially as populations age. Yet finding treatments has proven extremely difficult. A systematic review of research over two decades found that 98 Alzheimer’s drug candidates failed in clinical trials while only two succeeded. This highlights the enormous challenge of developing effective therapies.

What are brain organoids? (U.S. National Institute of Environmental Health Sciences)

One reason for this failure is that drugs that work in animals often do not work in humans. Mice and humans share many biological features, but important species differences mean animal models cannot fully reproduce the architecture and complexity of the human brain.

Traditional laboratory models also have other limitations. For example, many experiments rely on two-dimensional cell cultures, where cells grow in flat layers on plastic dishes. While useful, these systems lack the three-dimensional structure and cell-to-cell interactions found in real tissues. Without that complexity, they cannot accurately mimic many disease processes.

This is where organoids are transforming biomedical research.

In 2013, scientists demonstrated that brain organoids grown from human stem cells can self-organize into structures resembling parts of the developing brain. These “mini brains” contain multiple neural cell types and can mimic aspects of early brain development.

Researchers now use them to study conditions like autism, Alzheimer’s disease and amyotrophic lateral sclerosis (ALS).

Intestine, liver, kidney, pancreas

Beyond the brain, scientists have created organoids that resemble many other tissues, including the intestine, liver, kidney and pancreas.

An orange and green coloured image of mouse pancreatic ductal cells viewed through a microscope.
Mouse pancreatic ductal cells.
(Habib Rezanejad)

These models allow researchers to study diseases and test chemicals on human-like tissues rather than animals. For example, organoids could one day be used to screen chemicals for toxicity across multiple organs using cells derived from different individuals.

In my own research, my lab grows organoids from human and mouse pancreatic tissue to study cellular diversity and pancreatic inflammation. These models allow us to explore how different pancreatic cell types behave in three dimensions — something that would be impossible to observe in traditional flat cell cultures.

Potential for personalized medicine

A key advantage of organoids is their ability to capture human diversity. Laboratory mice used in experiments, on the other hand, are often genetically identical, which does not reflect the diversity of human populations.

Organoids can be grown from cells donated by individual patients, allowing researchers to study how diseases develop in different genetic backgrounds.

This opens the door to personalized medicine, where scientists test potential treatments on patient-derived organoids before giving them to patients.

Patient-derived organoids can predict how individuals might respond to certain drugs — for instance, responses to chemotherapy in metastatic colorectal cancer patients.

Organoids grown from many individuals, on the other hand, may provide a more realistic representation of how a population will respond to drugs. This helps researchers identify treatments that are more likely to succeed in clinical trials.

Overall, organoids are becoming powerful tools for drug discovery and safety testing.

Could this be the end of animal testing?

Some scientists believe organoids may replace animals altogether in certain areas of research. Organoid technology aligns with the “3Rs” principles in animal research — reduction, refinement and replacement — that aim to minimize the use of animals in science.

Reflecting this shift, the United States National Institutes of Health (NIH) recently announced it will prioritize research technologies that use human-based models rather than relying solely on animal experiments.

Pioneers in the field are optimistic. Hans Clevers, a leading scientist who helped develop gut organoids, has suggested that organoids could eventually replace animals in some forms of toxicology testing within the next few decades.

Still, organoids are not perfect

Although they are far more complex than traditional cell cultures, organoids remain simplified versions of real organs. Many lack blood vessels, which limits their size and maturity. They do not yet capture the full diversity of cell types found in human tissues, such as immune cells.

Studies have also shown that cells within organoids can experience stress due to laboratory growth conditions.

For now, organoids should be seen as powerful additions to the scientific toolbox rather than complete replacements for animal models.

Organoids are still an emerging technology, but they are already reshaping how scientists study human biology and disease. As the technology improves, these tiny lab-grown organs may help researchers reduce reliance on animal testing while bringing us closer to understanding — and treating — complex human diseases.

The Conversation

Habib Rezanejad receives Alberta Innovates Summer Research Studentship from Alberta Innovates for a research project at MacEwan University in 2025.

ref. Can ‘mini brains’ replace lab animals? Organoids are changing how scientists study disease – https://theconversation.com/can-mini-brains-replace-lab-animals-organoids-are-changing-how-scientists-study-disease-277611

In war-torn Iran, air pollution from burning oil depots and bombed buildings unleashes invisible health threats

Source: The Conversation – USA (3) – By Armin Sorooshian, Professor of Chemical and Environmental Engineering, University of Arizona

A woman sifts through the rubble in her home after it was damaged by a missile on March 15, 2026, in Tehran. Majid Saeedi/Getty Images

The waves of U.S. and Israeli bomb strikes in Tehran and Beirut, and Iran’s missile and drone attacks on neighboring countries in response, are damaging more than buildings – they are sending toxic debris into the air in cities that are home to millions of people.

Military strikes have hit Iran’s missile stockpiles, nuclear facilities and oil refineries. When a strike set fire to an oil depot, it sent toxic black clouds billowing over Tehran and created oily rain that settled on buildings, cars and people. Residents described having headaches and difficulty breathing.

As a chemical and environmental engineer who studies the behavior and effects of airborne particles, I have been following the damage reports to understand the health risks residents are facing as toxic materials get into the air. The risks come from many sources, from heavy metals in the munitions themselves to the materials sent airborne by what they blow apart.

A view acros the city's rooftops with multiple large smoke plumes rising.
Smoke plumes rise from several locations across Tehran following U.S. missile strikes on March 1, 2026.
Atta Kenare/AFP via Getty Images

The invisible enemy during war: Air pollution

A disaster’s effects on air quality and public health depend in large part on what is being destroyed.

The terrorist attacks on New York City’s World Trade Center on Sept. 11, 2001, were localized, but they ejected massive bursts of pollutants into the air. These included gases such as volatile organic compounds and particulates – often called aerosols – containing a myriad of substances, such as dust, polycyclic aromatic hydrocarbons, metals, asbestos and polychlorinated biphenyls.

These pollutants can harm the lungs, making breathing difficult, and worsen cardiovascular problems, contributing to heart attacks, among other health damage. Tiny particles smaller than 2.5 micrometers, called PM2.5, are especially harmful because they can travel deep into the human respiratory system. But larger particles can also bring major airborne health risks.

When buildings are heavily damaged or collapse, the rubble often contains crushed concrete, gypsum and carcinogenic fibrous materials, such as asbestos. Even after the initial dust settles, wind and other disturbances, including efforts to find survivors or clear the rubble, can send those materials back into the air, putting more people at risk.

Many rescue and recovery workers who responded to the World Trade Center collapse in 2001 developed chronic respiratory problems. That’s also a risk for people searching for survivors in bombed buildings after military strikes and later when cleaning up the debris.

Fires create additional hazards as vehicles, buildings and the chemicals and other materials in them burn. The January 2025 fires in Los Angeles sent a stew of dangerous particles and gases into the lower atmosphere. Studies have shown how lead particles that fell to the ground were kicked back up into the air again where people could inhale them, along with other contaminants.

Munitions and oil facilities

Military attacks degrade air quality in other ways. The Gaza Strip, Iraq, Kuwait, Ukraine and most recently Iran and surrounding countries have all faced extensive damage from munitions, which contain toxic materials. Bombs and artillery often contain explosives and heavy metals, such as lead and mercury, which also contaminate soil, water and the environment.

When oil storage facilities and pipelines are damaged, they emit an especially harmful cocktail of pollutants. This chemical blend includes airborne soot particles, which darken the sky and contribute to the “black rain” observed in Iran.

Thick smoke and flames over a row of burned out trucks.
A burning oil depot, hit by a military strike on March 8, 2026, sends black smoke over Tehran, causing black rain to fall in the region.
Hassan Ghaedi/Anadolu via Getty Images

During the Gulf War in 1991, downwind countries experienced similar polluted rain as Kuwait’s oil fields burned. The U.S. Department of Defense found that the smoke plumes contained sulfur dioxide and nitrogen oxides, among other gases and soot.

The severe consequences of environmental pollution during wars prompted the U.S. National Academies of Science, Engineering, and Medicine to publish a series of reports on Gulf War military veterans’ health, starting in the early 2000s. They documented illnesses soldiers suffered after being exposed to chemicals and heavy metals, including from oil well fires. They also examined scientific evidence on potential associations between pollution in war and reproductive and developmental effects in the veterans’ children.

Getting pollution out of the air

Nature, including rain and wind, can help reduce the pollution levels in the air.

Rain helps pull particles out of the air, depositing them back on the ground and surfaces. The raindrops form around particles and also collect more particles as they fall. However, rain has occurred only sporadically since the military attacks began in Iran.

And rain also contributes to runoff into streams, and pollutants can damage crops and contaminate waterways, soil and vegetation.

Wind can help blow pollutants out of an area, though at the expense of downwind sites.

A group of men walk through the remains of a building that collapsed. Several buildings around them are also damaged.
People inspect the rubble of a collapsed building on March 3, 2026, kicking up dust that can harm their health. U.S. Secretary of Defense Pete Hegseth said on March 13, 2026, that 15,000 targets had been hit since the U.S. and Israel began bombing Iran on Feb. 28.
Atta Kenare/AFP via Getty Images

Tehran has another challenge when it comes to pollution because of its terrain. The city is surrounded by mountains and prone to the effects of low-altitude temperature inversions in the wintertime, which concentrates pollutants even more by holding them closer to the ground. These attacks have been slightly outside the coldest periods for Tehran, allowing for deeper mixing of air, but the inversion still has an effect.

Can people in war zones protect their health?

People in war zones, where they are already under stress, can reduce their health risks by staying indoors in the days after military attacks, if possible. Keeping windows and doors closed can help reduce the amount of polluted ambient air that comes inside.

Indoor air quality is just as important as the air outside. For example, infants crawling on floors can be exposed to deposited particles with toxic materials that are tracked in or blow in under sills and doors, similar to wildfire smoke exposure.

As buildings continue to smolder and clearing debris sends harmful particles back into the air, the pollutants can also contaminate agriculture and waterways. People can try to avoid crops, water and seafood that were likely to have been affected by toxic airborne pollutants. However, getting information about risks gets harder in a time of war, and scarcity can leave people with few choices.

The Conversation

Armin Sorooshian does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

ref. In war-torn Iran, air pollution from burning oil depots and bombed buildings unleashes invisible health threats – https://theconversation.com/in-war-torn-iran-air-pollution-from-burning-oil-depots-and-bombed-buildings-unleashes-invisible-health-threats-278407

What happens to your brain in nature? The neuroscience explained

Source: The Conversation – Canada – By Mar Estarellas, Postdocotoral Researcher, Social and Transcultural Psychiatry, McGill University

Yoho National Park, Field, Canada. (Unsplash/Hendrik Cornelissen)

Have you ever felt calmer almost as soon as you step into the woods? Or maybe noticed your busy mind soften as you look out at the sea?

We have known for some time, and many of us sense it intuitively, that spending time in nature is good for us. Neuroscience is now enabling us to understand why, and what the brain is actually doing in those moments.

I was recently a co-author on a scoping review of the neuroscience of nature exposure, published in Neuroscience and Biobehavioral Reviews, together with colleagues from the Universidad Adolfo Ibañez, Chile, and Imperial College London, U.K.

We reviewed 108 peer-reviewed neuroimaging studies on nature exposure and we found a consistent picture. When people spend time in natural settings (or even view pictures of the outdoors), the brain tends to show signs of reduced stress, lighter mental effort and better emotional regulation.

Increases in alpha and theta waves

Many of us live in environments that keep the brain on alert through traffic, screens, noise, crowding and constant decision-making. And while cities are awesome human creations, they place heavy demands on our attention and stress systems.

A car drives down a city street at night.
The noise, lights and movement on a city street can be exhausting for our brains.
(Unsplash/Howei Wang), CC BY

Nature, by contrast, seems to offer a very different kind of input, and the brain responds accordingly.

One of the strongest findings comes from electroencephalogram (EEG) studies, which measure electrical activity in the brain. Across many experiments that we reviewed, natural settings were linked to increases in alpha and theta waves. These are often associated with relaxed wakefulness. Studies also often found decreases in beta activity, which is more closely related to active effort or cognitive load.

Put simply, the brain looks less “overworked” in nature.

But that doesn’t mean that it becomes passive or sleepy. We could understand it more as shifting into a mode of attention that is gentler and less effortful. For example, watching leaves move, listening to water or noticing changes in light engages the mind in a different way that a crowded street or a stream of notifications does.

Some studies suggest these effects can happen quickly. In several EEG experiments — both in the real world and virtual reality — changes showed up within a few minutes, sometimes even as little as three minutes.

Longer exposure often produced stronger effects, especially once people spent around 15 minutes in a more immersive setting.

Reduced activity in the amygdala

We also reviewed studies using functional magnetic resonance imaging (fMRI). These measure changes in blood flow linked to neural activity, allowing us to see which regions become more or less active.

One interesting finding was a reduced activity in brain regions involved in stress and rumination after time in nature. The amygdala, which helps detect threats and responds to stress, becomes less active after natural exposure. So does the subgenual prefrontal cortex, a region linked to repetitive negative thinking.

Other fMRI work points to changes in networks involved in attention and self-related thought, including parts of the default mode network. These regions are involved in self reflection, mind wandering and what we could call “the background stream of inner experience.”

In natural contexts, they reorganized in ways that supported a calmer and less scattered mental state.

A cascade of natural effects

Looking across the 108 studies, we found a broadly consistent pattern, which we summarize as a cascade of effects through which nature may influence the brain.

First, natural settings are often easier for the brain to process. Their shapes and rhythms frequently follow fractal patterns, like those seen in coastlines, leaves and clouds, which the brain appears to process efficiently.

This may reduce sensory and perceptual load. As that happens, stress-related systems begin to settle and the body can shift out of fight-or-flight mode.

Attention may then become less effortful, and emotional processing more stable. We describe this as a pathway linking perception, stress regulation, attention and self-related processing.

Could nature shape your brain anatomy?

Beyond the immediate effects of exposure, there is also evidence that nature may shape the brain over longer timescales. Structural MRI studies suggest that living in greener areas is associated with differences in brain anatomy, including greater grey matter volume and better white matter integrity in some populations.

These studies are mostly correlational, so caution is needed. They cannot prove that nature alone caused those differences. But they do raise the possibility that small restorative effects, repeated over months and years, may accumulate in ways that support cognition and resilience.

So when time outdoors makes you feel lighter, clearer or less caught in your own head, know this feeling is worth trusting. Your brain seems to be changing state.

And perhaps understanding a little more about how nature works on us, and how we in turn relate to it, can also help us protect it. Caring for nature is also a way of caring for ourselves and for each other.

The Conversation

Mar Estarellas does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

ref. What happens to your brain in nature? The neuroscience explained – https://theconversation.com/what-happens-to-your-brain-in-nature-the-neuroscience-explained-277332

How plant populations keep a genetic memory of the past

Source: The Conversation – Canada – By Daniel J Schoen, W.C. Macdonald Professor of Botany, McGill University

Jewelweed is found throughout eastern parts of North America. By studying jewelweed, researchers can understand how environmental changes affect plants over time. (Liz West), CC BY

Plants are usually seen as stationary life forms, quietly supporting environments. But plant communities and populations are far from static. They are constantly being shaped by the world around them.

One way is through local extinction — the loss of a local population from a specific patch of landscape. Another is through local colonization — the spreading or returning of plants to a landscape patch. In fact, many plant species are thought to be composed of metapopulations, which are sets of local populations connected by colonization, local extinction and population growth across a landscape.

If we were able to observe a metapopulation on the landscape over a time-lapse film covering several hundred years, we might see how the metapopulation changes and evolves as the film unfolds.

Of course, no such film exists, and time machines have not yet been invented, so understanding the forces that determine the history of metapopulations remains a challenge.

So, how can researchers understand the history of plant metapopulations? To do this, my colleague Rachel Toczydlowski and I turned to DNA sequence data with the plant jewelweed, or as botanists call it, Impatiens capensis.




Read more:
Tracking wildlife using DNA: A scientific breakthrough made with an Indigenous community


What is jewelweed?

Jewelweed is found throughout eastern parts of North America, including southern Québec and Ontario, and into the midwestern United States. This annual plant can form seeds through both cross-fertilization in normal flowers and through self-fertilization via a special type of closed flower that botanists refer to as a cleistogamous flower. Self-fertilization allows a single dispersing individual plant to establish a new population because it does not require a mate.

A bee gathering nectar from a yellow flower
Plants such as jewelweed also produce a type of flower that is closed and does not require pollinators.
(Rachel H. Toczydlowski)

The plant has the ability to found new populations from one or a few individuals via self-fertilization. The theory of metapopulations predicts that jewelweed as a species should be composed of a highly dynamic metapopulation where some patches have only been recently colonized, while others have been so for longer periods.

Jewelweed is typically found today in the forest fragments left over after agricultural and urban development. This type of habitat once existed as more continuous forest cover that blanketed much of the eastern and middle parts of North America prior to European colonization. This is especially true of the area in Wisconsin where we conducted our study, which is mostly farmland today, but retains island-like patches of more natural habitat.

Our research

We analyzed DNA sequence information obtained by sequencing the genomes of individual members of the population, and focused on how the individual genomes differ from one another.

Lining up the sequences and comparing them reveals differences in the DNA sequences of a sample of plants called single nucleotide polymorphisms (SNPs). These are positions in the sequence that differ from one another by possessing different nucleotides, the individual components of the sequence.

We then looked at the site frequency spectrum of each population, which shows how many SNPs are rare, how many are common and how many fall in between. Population founding events can change how common different SNPs are.

When a new population is founded by only a few individuals, many SNPs end up occurring at moderate frequencies. If the population then grows rapidly, new SNPs appear by mutation but remain rare, which changes the overall pattern of genetic variation.

And so, the form of the site frequency spectrum provides a kind of “genetic memory” of demographic events that gave rise to the individual-component plant populations within the metapopulation that we see today.

By applying this technique to DNA sequence data, we were able to detect significant differences in the demographic histories of the populations sampled. Some populations appeared to have only recently been founded and from a few individuals, whereas others appeared to be larger and more stable.

This pattern fits what is predicted by metapopulation theory for a species whose plants are capable of self-fertilization. The younger populations also exhibited loss of genetic diversity and higher levels of inbreeding compared to the older, more stable populations, which contained more diversity and were less inbred.

The higher inbreeding in younger populations suggests that they were founded by very few individuals and have not yet had enough time or gene flow from neighbouring populations to rebuild genetic diversity.

Importance for conservation

an orange-yellowish flower with red spots
Genetic variability is the foundation of adaptation. High levels of inbreeding can lead to weak or damaging traits being passed onto new generations.
(Unsplash/Jonathan Lim)

Genetic variability is the foundation of adaptation. High levels of inbreeding can lead to weak or damaging traits being passed on to new generations, which reduces the health of populations.

From a conservation standpoint, higher levels of diversity and lower levels of inbreeding are often desirable attributes.

They can enhance the adaptability and stability of populations, something that is becoming increasingly important as the climate changes.

Complicating our understanding of metapopulations, however, is the fact that not all landscapes are created equal. Some are more prone than others to disturbance and recovery, and when it comes to colonization of landscapes, not all plant species are created equal.

For instance, plants that can self-pollinate are more capable of founding a population from a few individuals and may be especially good colonizers compared with plants that require mates for seed production.

Understanding metapopulation history provides conservation managers with an additional perspective, especially when it comes to selecting the healthiest populations to conserve.

We may not have a time machine, but by analyzing the DNA of living populations, we can uncover the echoes of the past and understand their genetic implications for conservation.

The Conversation

Daniel J Schoen receives funding from the Natural Sciences and Research Council of Canada.

ref. How plant populations keep a genetic memory of the past – https://theconversation.com/how-plant-populations-keep-a-genetic-memory-of-the-past-276748

What the 2026 Oscars revealed about the current political mood in Hollywood

Source: The Conversation – UK – By Luis Freijo, Research Associate in Film Studies, King’s College London

The 2026 Academy Awards revealed a striking contradiction. Many of the winning films grapple with urgent contemporary issues, or difficult questions of historical memory. Yet their makers avoided following up on that political character in their acceptance speeches.

This paradox is revealing of the current political mood in Hollywood: filmmakers are willing to engage with politics in their work, but reluctant to raise their own voices.

It makes for a puzzling irony that contrasts with the attitude of, for instance, the music industry in the Grammy Awards. In a year of tariffs, Epstein files, US Immigration and Customs Enforcement (Ice) shootings and military interventions in Venezuela and Iran, the show’s host, comedian Conan O’Brien, kept the political references contained to harmless jokes.

For instance, O’Brien mentioned the tighter security for the gala, appearing to reference the FBI’s warning of possible drone attacks against the US west coast. But the nod quickly revealed itself as a pun about actor Timothée Chalamet’s recent declaration that “no one cares” about ballet and opera.

Even some of the more political speeches, such as Michael B. Jordan’s mention of the Black actors that preceded him when accepting the best actor Oscar, kept to industry boundaries.

Michael B. Jordan’s acceptance speech mentioned the Black actors he felt pathed the way for him.

Only comedian Jimmy Kimmel, whose show Jimmy Kimmel Live! has become strongly critical of President Donald Trump, obliquely mentioned his looming presence when presenting the best feature documentary award.

Politics of the nominated films

This attitude is glaringly detached from what this year’s nominees communicate in their films.

Bugonia, directed by Yorgos Lanthimos, poked at conspiracy theories through its kidnapping plot. The constant ping-pong hustle of Marty Supreme returned to the foundational moment of US capitalism in the 1950s and pointed out that it was already rotten way before Reaganomics and Trump. The Secret Agent, meanwhile, set its thriller story against the historical memory of the dictatorship in Brazil.

The two main winners of the night were also the most political films. Joyfully disguised behind the vampire film conventions and musical performances of Sinners lies a condemnation of ongoing racism in the US. But the film also proposes blues music as an alternative way to experience the world and create loving and protective connections between its inhabitants.




Read more:
Sinners: how real stories of Irish and Choctaw oppression inform the film


In this sense, Delroy Lindo’s performance as ageing blues singer Delta Slim centres the political core of the film. His retelling of a friend’s murder by lynching is first a lament, then rhythm and finally blues.

Lindo competed for best supporting actor against Sean Penn, whose winning work in One Battle After Another became relevant when it started to overlap with the media presence of Greg Bovino, commander-at-large of the US Border Patrol. Under Bovino’s command two US citizens were shot by Ice in Minneapolis in January.

Paul Thomas Anderson wins best director for One Battle After Another.

One Battle After Another recaptures the political spirit of 1970s US films such as The Three Days of the Condor (1975), Network (1976) and All the President’s Men (1976). These films reacted against the consequences of the Vietnam War and President Richard Nixon’s resignation in the 1970s. One Battle After Another brings to the present their activist attitude to oppose our contemporary political challenges.

The film’s chilling depiction of state violence against its own citizens connected with the events in Minneapolis and showed how relevant cinema can be when aimed at those in power. But the film had to speak for itself: its director, writer and producer, Paul Thomas Anderson, carefully avoided any direct mention of Trump, Ice or Minneapolis in his three acceptance speeches (for best adapted screenplay, director and film). And Sean Penn, whose political activism as a friend of Hugo Chávez or in favour of Ukraine has often made Hollywood uncomfortable, chose not to attend the ceremony.

Why nominees stayed silent

The reasons for the lack of politics at the awards may be found in the current industrial climate in the US. In September 2025, the Federal Communications Commission took Jimmy Kimmel Live! off the air for a few days, and continues to threaten to do it again. The industry chatter also believes Trump to be responsible for CBS’ decision to not renew The Late Show with Stephen Colbert, another critical outlet.

The possible acquisition, meanwhile, of Warner Bros. by Paramount, presided over by Trump’s ally David Ellison, follows Amazon’s purchase of MGM and Disney buying Twentieth Century Fox. The industrial landscape is concentrating in a handful of technological tycoons. They may may not take kindly to political activism when funding future projects.

The only political voice that was pointedly raised in the Oscars this year belonged to Spanish actor Javier Bardem.

Bardem appeared on stage to present the best international picture award sporting a lapel that said: “No a la Guerra” – no to war. He had worn the same lapel over 20 years ago when the Spanish Film Academy Awards in 2003 became a loud and clear indictment to Spain’s involvement in the Iraq war.

Bardem left a clear message as he introduced the award: “No to war and Free Palestine.” While films such as this year’s extraordinary intake can and do speak for themselves, the gravity of the moment requires that those who make them join with their own voices.

Bardem’s dissonant appeal reveals where Hollywood’s politics currently lie. They are caught between making committed films and a fear of what the country’s politics will bring.

The Conversation

Luis Freijo currently receives funding from the Volkswagen Foundation. He has previously received funding from the Arts and Humanities Research Council.

ref. What the 2026 Oscars revealed about the current political mood in Hollywood – https://theconversation.com/what-the-2026-oscars-revealed-about-the-current-political-mood-in-hollywood-278495